We have demonstrated that amino acids E (323), Y (324), E (330), and V (331) from the factor Va heavy chain are required for the interaction of the cofactor with factor Xa and optimum rates of prothrombin cleavage. We have also shown that amino acid region 332-336 contains residues that are important for cofactor function. Using overlapping peptides, we identified amino acids D (334) and Y (335...

Explaining the origin and evolutionary dynamics of the genetic architecture of adaptation is 8 a major research goal of evolutionary genetics. Despite controversy surrounding success of the attempts 9 to accomplish this goal, a full understanding of adaptive genetic variation necessitates knowledge about 10 C. Friedline Department of Biology Virginia Commonwealth University Richmond, VA 23284 E...

Explaining the origin and evolutionary dynamics of the genetic architecture of adaptation is 8 a major research goal of evolutionary genetics. Despite controversy surrounding success of the attempts 9 to accomplish this goal, a full understanding of adaptive genetic variation necessitates knowledge about 10 C. Friedline Department of Biology Virginia Commonwealth University Richmond, VA 23284 E...

Let D be a subset of the positive integers. The distance graph G(Z,D) has all integers as its vertices and two vertices x and y are adjacent if and only if |x − y| ∈ D, where the set D is called distance set. The vertex arboricity va(G) of a graph G is the minimum number of subsets into which vertex set V(G) can be partitioned so that each subset induces an acyclic subgraph. In this paper, the ...

Surgical stress and anaesthetics are able to suppress the immune system. This may accelerate the growth and metastasis of residual cancer cells. As Viscum album L. extracts (VA-E) are known to exert both effects, immunomodulating and apoptosis-inducing properties, a Good-Clinical-Practice-guided, prospective bi-centric phase II study was conducted to measure the influence of a perioperative int...

Given the putatively axiomatic connection between Irishness and Catholicism, it is not surprising that ubiquitous deathbed scene in Irish-American fiction imbricated with issue of ethnic identity. In romantic didactic fiction, scenes are just religiously coded, but also consolidate diasporic figurations Irishness. However, this article argues tradition only guise which feature fiction. As we sh...

December 15, 2008 J. Arrington, R. Dupré, D. Geesaman, K. Hafidi (spokesperson), R. J. Holt, D. H. Potterveld, P. E. Reimer, P. Solvignon Argonne National Laboratory, Argonne, IL W. Chen, H. Gao, X. Qian, Y. Qiang, Q. Ye Duke University, Durham, NC P. Markowitz Florida International University, Miami, FL C. .E. Keppel Hampton University, Hampton, VA G. Niculescu, I. Niculescu James Madison Univ...

H. Tan, W. Chen, P. Hu, G. W. Miller, T. A. Altes, J. F. Mata, E. E. de Lange, G. D. Cates, R. F. Lee, C. H. Meyer, and J. P. Mugler III Electrical Engineering, University of Virginia, Charlottesville, VA, United States, Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, now with GE Healthcare, now with Beth Israel Deaconess Medical Center, Department of Radiolo...