Abnormal uterine bleeding is a frequent debilitating symptom resulting in unnecessary, incorrect and expensive treatment and invariably ends up in surgical treatment with its attendant risk of morbidity and mortality. It occurs in 9-14% of women between menarche and menopause, significantly impacting quality of life and imposing financial burden (3). After excluding the structural causes of AUB...

Dysfunctional uterine bleeding (DUB) is a common presentation in the emergency department and has a wide differential. Most presentations of DUB are in hemodynamically stable patients and can be evaluated as an outpatient. Uterine arteriovenous malformation (AVM) is one presentation that can result in a life-threatening medical emergency with unexpected sudden and massive vaginal bleeding. We d...

A clinical appraisal and clinical application of: DeVore GR, Owens O, Kase N. treatment of dysfunctional uterine bleeding--a double This appraisal identifies significant statistical irregularities in the study. A reworking of the study's statistics lea different from that put forth by the authors of this paper: intravenous estrogen therapy is not, in fact, significantly more compared to placebo...