Discretization errors due to the digitization of computed tomography images and the calculation grid are a significant issue in radiation therapy. Such errors have been quantitatively reported for a fixed multifield intensity-modulated radiation therapy using traditional linear accelerators. The aim of this study is to quantify the influence of the calculation grid size on the dose distribution...

PURPOSE To evaluate the effects of rectal enemas on rectal doses during radical high-dose-rate (HDR) intracavitary cervical brachytherapy (BT). MATERIAL AND METHODS Twenty patients suffering from cervical cancer and treated with external beam radiotherapy and HDR-BT were included in a prospective trial. The first brachytherapy fraction was considered the basal status, and patients were instru...

The response of Desulfovibrio vulgaris Hildenborough (DvH), a sulphate-reducing bacterium, to nitrate stress was examined using quantitative proteomic analysis. DvH was stressed with 105 mM sodium nitrate (NaNO(3)), a level that caused a 50% inhibition in growth. The protein profile of stressed cells was compared with that of cells grown in the absence of nitrate using the iTRAQ peptide labelli...

OBJECTIVES The aim of this study was to define a method to evaluate the total dose delivered to the rectum during the whole treatment course in six patients undergoing irradiation for prostate cancer using an offline definition of organ motion with images from a cone beam CT (CBCT) scanner available on a commercial linear accelerator. METHODS Patient set-up was verified using a volumetric thr...

Background: Some ssues in human body are radiobiologically different from water and these inhomogeneity must be considered in dose calcula on in order to achieve an accurate dose delivery. Dose verifica on in complex radia on therapy techniques, such as intensity‐modulated radia on therapy (IMRT) calls for volumetric, ssue equivalent and energy independent dosimeter. The purpose of this study i...

Telah dilakukan penelitian mengenai distribusi dosis radiasi foton pada Treatment Planning System (TPS) menggunakan teknik Three Dimension Conformal Radiotherapy (3DCRT) dan Intensity Modulation (IMRT) untuk terapi kanker serviks, ini bertujuan mengetahui yang mencangkup Target Volume (PTV) ) Cakupan melalui Conformity Index (CI) Homogeneity (HI) serta Normal Tissue to Integral Dose (NTID) jari...

Radiation pneumonitis (RP) is one of the common side effects radiotherapy in thoracic region. Radiomics and dosiomics quantifies information implicit within medical images dose distributions. In this study we demonstrated prognostic potential radiomics, dosiomics, clinical features for RP prediction. Radiomics, dose-volume histogram (DVH) metrics, parameters were obtained on 314 retrospectively...

The purpose of this study was to evaluate the accuracy of commercially available software, using patient DVH-based QA metrics, by investigating the correlation between estimated 3D patient dose and magnitude of MLC misalignments. We tested 3DVH software with an ArcCHECK. Two different calculating modes of ArcCHECK Planned Dose Perturbation (ACPDP) were used: "Normal Sensitivity" and "High Sensi...