Inference based on the likelihood function owes much to theory developed some decades ago. What is the current role of likelihood in developing strategies for the analysis of very large data sets, often with very high dimension, and complex dependencies? This paper considers some aspects of this question with emphasis on problems in stochastic modelling, estimating equations, and surveymethodol...

the nomad communities played an important role in the socio-economic status of the iranian society from the beginning of the twentieth century. following the political events of reza shah such as settling strategy, the nomads lost their importance and marginalized. the present paper aims study the social and cultural transitions among the turkman tribe to find out how settling strategy led to t...

for years, the role of cerebellum was believed to be limited to motor functions. only since almost two decades ago, a new concept about cerebellum and its contribution to non-motor functions including cognition and emotion started to emerged. during the recent years, numerous studies have focused on the cerebellar non-motor functions with their results providing supportive evidence on this view...

“I will not work for the present no more, I am working for the future”said Tesla to journalists gathered in New York City more than seven decades ago. – “The future is mine!” Inventor of alternating current, polyphase engines and generator, reversible magnetic field, radio, teleautomatics, inventor, on whose patents energetics of XX century is properly based, worked alone on explanation of cosm...

Gene therapy, though first proposed as a concept decades ago, has faced numerous setbacks in the form of serious adverse effects during early clinical trials. However, recent successes field applied to neuromuscular disease, blindness, and cancer have stimulated renewed interest application gene therapy for clinically intractable diseases. Neurological diseases, which been proven be some most l...

During the past three decades, every aspect of cardiomyopathy has undergone dramatic change. When examining the literature on the physiological aspects of the failing heart, one immediately recognises that South Africa has made a contribution: Brink, Bester and Lochner evaluated the possible therapeutic aspects of the Bowditch phenomenon and myocardial energetics in cardiomyopathy almost four d...