Aqueous extract of leaves of M. oleifera was investigated and rationalised for its wound healing activity. The aqueous extract was studied at dose level of 300 mg/kg body weight using resutured incision; excision and dead space wound models in rats. Significant increase in wound closure rate, skin-breaking strength, granuloma breaking strength, hydroxyproline content, granuloma dry weight and d...

STUDY OBJECTIVE To compare three dressing types in terms of their ability to protect against infection and promote healing, patient comfort, and cost-effectiveness. DESIGN Prospective, randomized controlled trial. SETTING Major metropolitan, academically affiliated, tertiary referral center. PATIENTS Seven hundred thirty-seven patients were randomized to receive a dry absorbent dressing (...

The aqueous extract of C. papaya fruit (100 mg kg(-1) day(-1) for 10 days) was evaluated for its wound healing activity in streptozotocin-induced diabetic rats using excision and dead space wound models. Extract-treated animals exhibited 77% reduction in the wound area when compared to controls which was 59%. The extract treated wounds were found to epithelize faster as compared to controls. Th...

BACKGROUND Contaminated traumatic open orthopedic wounds are frequently complicated by polymicrobial contamination and infection. In high-risk wounds, the standard of care comprises debridement and irrigation combined with antibiotics which can be applied directly or combined with systemic antibiotics. Recently, bioabsorbable chitosan sponges have been shown to be an effective single-agent deli...

The effect of dry powder povidone-iodine (Disadine D.P.) on wound healing was assessed experimentally and clinically. It did not interfere with wound healing macroscopically, histologically or mechanically in Wistar rats. One hundred and one patients undergoing 'clean' elective surgery were included in the controlled clinical study and povidone-iodine did not affect wound healing in any way. In...

Traumatic cataract was induced in rat and rabbit. The progression of the posterior subcapsular cataract and the wound healing were followed by quantitative microradiography. This method makes it possible to determine the dry mass content and to calculate the refractive indices in the lens. In the injured rat lens a reduced dry mass concentration was determined in both the wound region and the p...

Traumatic tympanic membrane (TM) perforations heal spontaneously ranging from 78.7% to 88%. Otologists recommend a golden rule, keep the ear dry, as an important factor influencing TM healing. This way, Araujo et al., in their article “The Topical Use of Insulin Accelerates the Healing of Traumatic Tympanic Membrane Perforations,” describe a control group of Wistar rats in which traumatic perfo...

morinda citrifolia (noni) has been traditionally used for bone and wound healing.   the present study was carried out to investigate the effect of morinda citrifolia leaves on experimental wounds and lipid peroxide levels in rats. effect of aqueous extract of leaves of morinda citrifolia (200 mg/kg) on excision, resutured incision and dead space wound models were studied. measurement of blood m...

Objective: To evaluate wound healing activity of ethanolic extract of Jasminum grandiflorum Linn. (J. grandiflorum) flowers in diabetic rats. Materials and Methods: Streptozotocin-induced diabetic Wistar albino rats were divided into six groups (n=6).Three groups – diabetic control, positive control (that received Glibenclamide) and treatment (that received J. grandiflorum Linn. Flower extract...

Morinda citrifolia (Noni) has been traditionally used for bone and wound healing.   The present study was carried out to investigate the effect of Morinda citrifolia leaves on experimental wounds and lipid peroxide levels in rats. Effect of aqueous extract of leaves of Morinda citrifolia (200 mg/kg) on excision, resutured incision and dead space wound models were studied. Measurement...