Diquafosol is a drug used for dry eye treatment with a novel mechanism of action. It stimulates the secretion of tear fluid and mucin on the ocular surface, thus enabling us to selectively treat the tear film layer, playing an important role in the establishment of the concept of "Tear Film Oriented Therapy (TFOT)", an effective therapeutic approach to dry eye in Japan. The 3% diquafosol ophtha...

PURPOSE To investigate the association of dry eye disease with sleep quality. METHODS In 2011, a cross-sectional survey was conducted among all the employees, mainly young and middle-aged Japanese office workers, who used visual display technology, at a company in Osaka, Japan (N=672; age range =26-64 years). The participants were classified according to the Japanese dry eye diagnosis criteri...

PURPOSE Dry eye disease is defined as a multifactorial disease of tears and ocular surfaces that causes discomfort, visual disturbance, and tear film instability with potential damage to the ocular surface. This study aimed to determine dry eye findings in patients with depression. MATERIAL AND METHODS There were 40 patients with depression aged 18-65 years old. A comprehensive ophthalmic exa...

AIMS To determine the incidence, natural course, and severity of dry eye occurring or worsening after haematopoietic stem cell transplantation (SCT). METHODS At a tertiary care hospital, 53 patients undergoing allogeneic or autologous SCT followed by at least 180 days of follow up were studied prospectively. Examination included grading of symptoms of dry eye, evaluation of ocular surface, te...

INTRODUCTION Diabetes may affect the human body's systems and organs, including the eye. Diabetic retinopathy is the 5th leading cause of blindness globally. Diabetic subjects demonstrated dry eye symptoms that were also supported by the low values of the clinical tests. PURPOSE This study aimed to compare the dry eye symptoms and signs between diabetics and non-diabetics and tear functions b...

PURPOSE To assess current practice patterns for dry eye patients in South Korea and to evaluate the preference according to the ages and clinic types of physicians. METHODS Dry eye patients (n = 1,612) were enrolled in this multicenter cross-sectional, observational study. The severity level of dry eye patients was classified based on the Korean guidelines for dry eye treatment. The medical r...

Just as the name suggests, this condition makes the eyes feel dry, scratchy, and gritty. Other symptoms include burning, stinging, itching, pain, sensitivity to light, redness, blurry vision, and the feeling that there is a speck of dirt in the eye. There may also be a stringy discharge from the eyes. And though it may seem strange, dry eye can cause the eyes to water. "This can happen because ...

PURPOSE To determine the most effective objective tests, applied singly or in combination in the diagnosis of dry eye disease. METHODS Two groups of subjects--41 with dry eye and 32 with no ocular surface disease--had symptoms, tear film quality, evaporation, tear turnover rate (TTR), volume and osmolarity, and meibomian gland dropout score assessed. RESULTS The subjects with dry eye had TT...