It is known that plant-based ethnomedicine represented the foundation of modern pharmacology and that many pharmaceuticals are derived from compounds occurring in plant extracts. This track still stimulates a worldwide investigational activity aimed at identifying novel bioactive products of plant origin. However, the discovery that endophytic fungi are able to produce many plant-derived drugs ...

Catherine A. Heyneman is the director of the Idaho Drug Information Service and an assistant professor of Pharmacy Practice at the Idaho State University College of Pharmacy, Pocatello, Idaho. Medicinal herbs have been used since the beginning of recorded time. Approximately one quarter of prescription drugs on the market today are still derived from plant products (eg, digoxin from the foxglov...

Only a small fraction of the immense diversity of plant metabolism has been explored for the production of new medicines and other products important to human well-being. The availability of inexpensive high-throughput sequencing is rapidly expanding the number of species that can be investigated for the speedy discovery of previously unknown enzymes and pathways. Exploitation of these resource...

background: poisoning is one of the main causes of visits to emergency departments and hospitals in iran. drug and poison information centers (dpic) are reliable sources to guide poisoned patients and provide information about pharmaceutical agents. this study was designed to analyze recorded phone calls to iran dpics during 2011-2012. methods: this was a retrospective study on phone calls to d...

An important element of drug development using plants is the accumulation and analysis of pertinent research data and purported ethnomedical (folkloric) uses for plants. Due to the quantity of information frequently available in the literature and its appearance over many years from worldwide sources, this information is best stored and analyzed by computers, There are 10 automated data bases t...

biofilm of pseudomonas aeruginosa, an opportunistic pathogen, can cause serious health problems, such as chronic infections, especially in immunocompromised patients. many studies have suggested administration of new generation of antibiotics, as p. aeruginosa biofilms have developed high resistance to antimicrobial drugs. this study reports the inhibitory effect of three medicinal plant extrac...

Cancer is one of the leading causes of death and globally the numbers of cases of cancer are increasing gradually. There are several medicines available in the market to treat the various types of cancer but no drug is found to be fully effective and safe. The major problem in the cancer chemotherapy is the toxicity of the established drugs. However plants and plant derived products have proved...

Medicinal plants have historically proven their value as a source of molecules with therapeutic potential, and nowadays still represent an important pool for the identification of novel drug leads. In the past decades, pharmaceutical industry focused mainly on libraries of synthetic compounds as drug discovery source. They are comparably easy to produce and resupply, and demonstrate good compat...

The multigene family of enzymes known as glycosyltransferases or popularly known as GTs catalyze the addition of carbohydrate moiety to a variety of synthetic as well as natural compounds. Glycosylation of plant secondary metabolites is an emerging area of research in drug designing and development. The unsurpassing complexity and diversity among natural products arising due to glycosylation ty...