نتایج جستجو برای: dpp6

تعداد نتایج: 82  

Journal: :The Biochemical journal 2003
Shu Y Qi Pierre J Riviere Jerzy Trojnar Jean-Louis Junien Karen O Akinsanya

Two dipeptidyl peptidase IV (DPPIV, DPP4)-related proteins, DPP8 and DPP9, have been identified recently [Abbott, Yu, Woollatt, Sutherland, McCaughan, and Gorrell (2000) Eur. J. Biochem. 267, 6140-6150; Olsen and Wagtmann (2002) Gene 299, 185-193; Qi, Akinsanya, Riviere, and Junien (2002) Patent application WO0231134]. In the present study, we describe the cloning of DPP10, a novel 796-amino-ac...

Journal: :Circulation. Arrhythmia and electrophysiology 2013
Louise R A Olde Nordkamp Arthur A M Wilde Jan G P Tijssen Reinoud E Knops Pascal F H M van Dessel Joris R de Groot

BACKGROUND Indications for prophylactic implantable cardioverter-defibrillator (ICD) therapy in patients with inherited cardiac diseases stem from observational studies and are uncertain. This study evaluates the efficacy and harm rate of ICD implantations for primary prevention compared with secondary prevention in inherited cardiac diseases. METHODS AND RESULTS Between January 1, 1993, and ...

Fan W, Li L Wang P Yin Ch

Background: Aberrant chromosomes can cause azoospermia but little is known about its molecular mechanism. Our aim is to explore any possible genetic defective to explain a given male infertility. Materials and Methods: An azoopsermic male was identified in a 23 years old male. G-banding and FISH confirmed the karyotype as chromosome insertion (18:7) (q22.1; q36.2q21.11). NGS was performed to an...

2013
Lin Lin Wei Sun Ben Throesch Faith Kung Jameice T Decoster Cory J Berner Richard E. Cheney Bernardo Rudy Dax A Hoffman

Dipeptidyl-peptidase 6 is an auxiliary subunit of Kv4-mediated A-type K(+) channels that, in addition to enhancing channel surface expression, potently accelerates their kinetics. The dipeptidyl-peptidase 6 gene has been associated with a number of human central nervous system disorders including autism spectrum disorders and schizophrenia. Here we employ knockdown and genetic deletion of dipep...

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