نتایج جستجو برای: doxycycline hyclate
تعداد نتایج: 5120 فیلتر نتایج به سال:
BACKGROUND Recent studies have raised concern about efficacy of azithromycin for Chlamydia trachomatis infection. Research investigating new antibiotic regimens for chlamydia has been sparse, especially regimens that may reduce adherence difficulties with the recommended twice-daily doxycycline regimen. METHODS We conducted a randomized, double-blind, double-dummy, active-controlled, multicen...
BACKGROUND This research report evaluates clinical changes resulting from local delivery of doxycycline hyclate (DH) or traditional scaling and root planing (SRP) in a group of patients undergoing supportive periodontal therapy (SPT). METHODS In all, 141 patients received either DH (67) or SRP (74) treatment in sites > or =5 mm on one-half of their dentition at baseline and month 4. RESULTS...
E. JANTRATID, S. STRAUCH, C. BECKER, J.B. DRESSMAN, G.L. AMIDON, H.E. JUNGINGER, S. KOPP, K.K. MIDHA, V.P. SHAH, S. STAVCHANSKY, D.M. BARENDS Institute of Pharmaceutical Technology, Goethe University, Frankfurt am Main, Germany Bayer Technology Services GmbH, Leverkusen, Germany College of Pharmacy, University of Michigan, Ann Arbor, Michigan Faculty of Pharmaceutical Sciences, Naresuan Univers...
Broad-spectrum antimicrobial doxycycline acts as an inhibitor of protein synthesis and it is widely used in the clinical treatment various infections by microorganisms that are sensitive to drug, well animal feed. Its liposolubility guarantees its high tissue bioavailability, being associated with several biochemical changes organism potentially adverse effects on reproduction. This study aims ...
A number of ways have been investigated for administration of antibacterial agents in dealing of plaque-initiated periodontal disease. These include prolonged release intrapocket devices which are inserted at diseased sites. Intrapocket drug delivery system was designed which contain Doxycycline Hyclate an antibacterial agent. The formulations were so developed with an aim to reduce the dose of...
A number of ways have been investigated for administration of antibacterial agents in dealing of plaque-initiated periodontal disease. These include prolonged release intrapocket devices which are inserted at diseased sites. Intrapocket drug delivery system was designed which contain Doxycycline Hyclate an antibacterial agent. The formulations were so developed with an aim to reduce the dose of...
Prion diseases are transmissible neurodegenerative disorders of humans and animals for which no effective treatment is available. Conformationally altered, protease-resistant forms of the prion protein (PrP) termed PrP(Sc) are critical for disease transmissibility and pathogenesis, thus representing a primary target for therapeutic strategies. Based on previous findings that tetracyclines rever...
The range of doxycycline drugs on the pharmaceutical market Ukraine is very limited and represented by solid forms (capsules tablets) while a rapid effect maximum bioavailability drug can be provided parenteral administration. object study hyclate in form lyophilisate to prepare solution for injections. During development it was taken into account that aqueous pH dependent tends shift during lo...
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