Viêm não do Rickettsia ở trẻ em là một bệnh lý hiếm gặp. Bệnh có triệu chứng lâm sàng và cận không đặc hiệu, thương tổn nhiều các cơ quan khác nhau, chẩn đoán ca chủ yếu dựa vào dịch tễ, vết loét hiệu xét nghiệm tìm căn nguyên. Điều trị bằng kháng sinh như Tetracyclin, Chloramfenicol, Doxycyclin vẫn đạt quả tốt. Chúng tôi báo cáo trường hợp nam, 7 tháng tuổi, được viêm Rickettsia. Trẻ đủ tiêu c...

The endoglin heterozygous (Eng(+/-)) mouse, which serves as a model of hereditary hemorrhagic telangiectasia (HHT), was shown to express reduced levels of endothelial NO synthase (eNOS) with impaired activity. Because of intricate changes in vasomotor function in the Eng(+/-) mice and the potential interactions between the NO- and prostaglandin-producing pathways, we assessed the expression and...

Our previous results that IFI16 is involved in p53 transcription activity under conditions of ionizing radiation (IR), and that the protein is frequently lost in human breast cancer cell lines and breast adenocarcinoma tissues suggesting that IFI16 plays a crucial role in controlling cell growth. Here, we show that loss of IFI16 by RNA interference in cell culture causes elevated phosphorylatio...

this paper presents a case-report of cutaneous actinomycosis due to actinomyces viscosus in a 22 year old man, hospital staff from tehran with multiple fistulous tracts in his right hand and a history of skin injury due to thorn of plant. diagnosis was based on the observation of gram positive coccoid, diphtheroid and long branching filaments in direct examination of pus from fistulous tracts a...

Methods Eight female Large White-Landrace pigs (33.9 ± 2.1 Kg) were anesthetized, tracheally intubated and connected to a mechanical ventilator. Ultrasound-guided arterial cannulation was performed, and a Swan-Ganz catheter was inserted into the jugular vein for hemodynamic monitoring. Following surgical preparation, and 4 hours thereafter, 15 mL of 10 cfu/mL of S. pneumonia serotype 19A, resis...

Current concepts of diagnosis and treatment of CAP are risk stratified and adapted to the national resistances of important pathogens. Thorough surveillance systems have to be implemented in all countries. The risk of patients can be assessed reliably with a limited number of clinical data (CRB-65 score). Extended microbiological and laboratory diagnosis is recommended for hospitaliszed patient...