The branch chain amino acid leucine is a potent stimulator of protein synthesis in skeletal muscle. Leucine rapidly enters the cell via the L-Type Amino Acid Transporter 1 (LAT1); however, little is known regarding the localisation and distribution of this transporter in human skeletal muscle. Therefore, we applied immunofluorescence staining approaches to visualise LAT1 in wild type (WT) and L...

Osteoid osteoma (OO) is a relatively common skeletal neoplasm, frequently involves long bones. OO of rib is extremely rare, including 0.23-2% of OO cases. Most of them arose in posterior arc, frequently in its head or neck and might lead to painful scoliosis. Involvement of anterior aspect of a rib is extremely rare. Skeletal scintigraphy is highly sensitive for detection of OO. “Doubl...

skeletal muscle is a highly differentiated tissue with very specific functions which has low potential of regeneration. skeletal muscle injuries especially in athletes almost have lead to muscular dysfunctions and healing may be prolonged for several years. therefore, working on skeletal muscle differentiation remained an importance in biomedical researches. adipose derived stem cells (adscs) a...

Skeletal muscle cell-derived grafts in the heart may benefit myocardial performance after infarction. Several studies have suggested that skeletal muscle stem cells (satellite cells) from adult muscle undergo transdifferentiation into cardiomyocytes after grafting into the heart, but expression of cardiac markers in graft cells has not been rigorously confirmed. To determine the fate of satelli...

Background. In morphometric and allometric analysis, the degree of variation attributable to non-biological causes is ignored. The effects this on subsequent statistical analyzes are unknown. It unclear whether sample conservation induces substantial in shape such affects inference interpretation. Therefore, fish skeletal studies, routinely prepared for osteological studies using a common proce...

The molecular machinery underlying neurotransmitter receptor immobilization at postsynaptic sites is poorly understood. The NMDA receptor subunit NR1 can form clusters in heterologous cells via a mechanism dependent on the alternatively spliced C1 exon cassette in its intracellular C-terminal tail, suggesting a functional interaction between NR1 and the cytoskeleton. The yeast two-hybrid screen...