objective(s): the present study aims to study the alteration of glutamatergic transmission in the dorsal horn neurons and the effect of gabapentin on oxaliplatin-induced neuropathic pain in rats. materials and methods: oxaliplatin (5 mg/kg) or saline was administered to adult male sprague-dawley rats.  gabapentin (60 mg/kg, ip) or vehicle was injected daily. mechanical allodynia was assessed us...

Objective(s):The present study investigated the effect of long-term mild cerebral hypoperfusion induced by permanent unilateral (right) common carotid artery occlusion (UCO) on the dorsal hippocampal neurons in rats. Materials and Methods:Sixty four male Sprague-Dawley rats aged 4 months were divided into two groups of sham and UCO. These two groups were further divided into 4 sets of histopath...

Recent studies have revealed that noxious visceral inputs travel in the dorsal column pathway, and interactions between colorectal noxious and tactile inputs occur in the ventrobasal thalamus. This investigation was to test whether the somatovisceral interactions also take place in the dorsal column nuclei (DCN). Forty-five single DCN neurons of anesthetized rats responsive to colorectal disten...

AbsractAll perilunate fracture-dislocations combine bone avulsions, ligament disruptionand fractures in different forms. The most frequent pattern is the dorsal transscaphoidperilunate fracture-dislocation. The reported risk of missed initial diagnosisin perilunate dislocations is as high as 20%. Concerning pathomechanics of theperilunate fracture-dislocation, it should be noted that most dorsa...

Recent studies have revealed that noxious visceral inputs travel in the dorsal column pathway, and interactions between colorectal noxious and tactile inputs occur in the ventrobasal thalamus. This investigation was to test whether the somatovisceral interactions also take place in the dorsal column nuclei (DCN). Forty-five single DCN neurons of anesthetized rats responsive to colorectal disten...

introduction: to recognize the myelinated nerve fibers of the external capsule in human brain. materials and methods: 10 adult and normal brains (20 hemispheres) from both sexes were studied using 15 mm serial sections in all three cardinal planes after fixation and processing. these sections were stained by klüver - barrera and heidenhain - woelcke methods. results: some fibers from different ...