Abstract Dorema (Apiaceae) includes 12 species distributed in the Irano-Turanian region. The genus differs from other genera of subfamily Apioideae having paniculate inflorescences with simple umbels. Recently, molecular phylogenetic analyses placed six Dorema, including generitype, Ferula , thus subsuming former into synonymy latter. remaining congeners have not been yet included analyses. Her...

Penicillium glabrum is a filamentous fungus frequently involved in food contamination. Numerous environmental factors (temperature, humidity, atmospheric composition, etc.) or food characteristics (water activity, pH, preservatives, etc.) could represent potential sources of stress for micro-organisms. These factors can directly affect the physiology of these spoilage micro-organisms: growth, c...

In recent decades, xylanases have been used in many processing industries. This study describes the xylanase production by Penicillium glabrum using brewer's spent grain as substrate. Additionally, this is the first work that reports the purification and characterization of a xylanase using this agroindustrial waste. Optimal production was obtained when P. glabrum was grown in liquid medium in ...

BACKGROUND Dorema aucheri is a plant of Apiaceae family which is used widely in some states of Iran. Different extracts and essential oil of Dorema species contain flavonoids and cumarin compounds which have anti-hypertensive, cholesterol- and triglycerides-lowering properties. This study was undertaken to evaluate the genotoxic properties of hydroalcoholic and aqueous extracts of D. aucheri on...

Some Dorema species are used in Persian traditional medicine. In the present study the total extract from the roots of Dorema hyrcanum Koso-Pol. was investigated for its in-vitro (pLDH assay) and in-vivo (Peters' 4-days suppressive test) antiplasmodial effects and assessed for cytotoxicity against the normal cell line MDBK (MTT test). The IC50 values for a chloroquine- sensitive (3D7) and a chl...

this study investigated the anticonvulsant activity and possible mechanism of action of an aqueous solution of dorema ammoniacum gum (dag) which has been used traditionally in the treatment of convulsions.in this study, the anticonvulsant activity of dag was examined using the pentylentetrazole (ptz) model in mice. thirty male albino mice were divided randomly and equally to 5 groups, and pretr...

In the search for new marine derived antibiotics, 43 epi- and endophytic fungal strains were isolated from the surface or the inner tissue of different marine plants and invertebrates. Through preliminary and secondary screening, 10 of them were found to be able to produce broad-spectrum antimicrobial metabolites. By morphological and molecular biological methods, three active strains were char...