Introduction. Although commonly classified as a Negative Concord (NC) language since it readily allows single negation readings of Negative Concord Items (NCI) sequences (1c), French has widely been acknowledged to also tolerate Double Negation (DN) or Negative Discord, albeit as a marked option (De Swart, Corblin, 1996). This DN tolerance, diagnosed by Zeijlstra (2004) as a symptom of the stil...

diabetic nephropathy is common in mazandaran and a significant number of patients under chornic hemodialysis are diabetics. the present study was designed to study the prevalence and predisposing factors of diabetic nephropathy (dn) in mazandaran. methods: during a 20 months period from june 1993 through december 1994, 490 (350 female, 140 male) cases of non-insulin dependent diabetes mellitus ...

Ets transcription factors are associated with tumor malignancy. We reported previously that the stable transfection of the dominant-negative form of Ets-1 (Ets-DN) in the glioma cell line U251 induced down-regulation of urokinase-type plasminogen activator mRNA expression and invasiveness (M. Nakada et al., J. Neuropathol. Exp. Neurol., 58: 329-334, 1999). Here we analyzed effects of Ets-DN exp...

1. ANS fluorescence change at various energized stages of mitochondria was investigated. 2. Freshly prepared mitochondria manifest ANS fluorescence change during anaerobic-aerobic transition, but aged and inner mitochondrial membrane show remarkable changes. 3. These data suggest that freshly prepared mitochondria or those in energized state exhibit less hydrophobic environments or decrease the...

Number skills are popularly bound to arithmetic knowledge in its symbolic form, such as “five + nine = fourteen,” but mounting evidence suggests that these symbolic relations are actually grounded, i.e., computed (see Harnad, 1990) on noisy internal magnitude representations that bear our general understanding of numbers and further improve with math experience (Figure 1). Multiple lines of evi...

Emerging evidence suggests that dyslipidemia is an independent risk factor for diabetic neuropathy (DN) (reviewed by Vincent et al. 2009). To experimentally determine how dyslipidemia alters DN, we quantified neuropathic symptoms in diabetic mice fed a high-fat diet. Streptozotocin-induced diabetic C57BL/6 mice fed a high-fat diet developed dyslipidemia and a painful neuropathy (mechanical allo...

Evidence of Earlyto Mid-Cryogenian (c. 780 Ma and c. 740 Ma) glacial activity is summarized for the northern Arabian–Nubian Shield (ANS), including structural framework, stratigraphy, lithological descriptions and relationships with younger and older units, banded iron formation chemostratigraphy, other characteristics, geochronological constraints, and discussion. The ANS is a broad tract of j...

Le lupus érythémateux systémique (LES) juvénile est une connectivite rare, d’évolution plus sévère que chez l’adulte. Les cas familiaux sont exceptionnels. Il s’agissait de deux familles (5 patients atteints), chez qui on a objectivé un LES juvénile chez deux sœurs âgées de 14 ans et 6 ans respectivement chez la première famille, deux frères, âgés de 20 ans et 6 ans respectivement plus une sœur...

Diabetic nephropathy (DN) is the leading cause of ESRD in the United States, and its global occurrence is rising rapidly. As evidencedby thewide spectrumofdebilitatingmacroand microvascular complications that patients eventually experience, the vascular endothelium is a prominent target of longstanding diabetes. In the hunt for breakthrough discoveries that could someday transform the treatment...