Background: Bone sarcomas are usually aggressive tumors treated by multimodality approaches. Early detection of residual or recurrent tumor tissue after treatment is important in the management of these patients. This is currently achieved by clinical examination, diagnostic radiological procedures, radionuclide imaging techniques and detailed histological examination. Tumor response to preoper...

The Gorham-Stout disease is a very rare condition, characterized by lymphovascular proliferation and massive bone resorption. We present a 48-year-old male patient with osteolysis involving the left femoral head and neck, as well as to the ipsilateral acetabulum. Besides the morphological imaging, he underwent bone scintigraphy, technetium-99m-V-dimercaptosuccinic acid [99mTc(V)-DMSA] single ph...

We present a case of phyllodes tumor of the breast in a 78-year-old woman evaluated with Tc-99m (V)DMSA and Tc-99m MIBI scintimammography, acquired in separate sessions (10 and 60 min post-injection). Tc-99m (V)DMSA was accumulated intensely within the mass [tumor to background ratio (T/B) >3], whereas Tc-99m MIBI had significantly lower uptake (T/B 1.9). Histology revealed a phyllodes tumor (m...

Renal osteodystrophy (ROD) is a common and serious complication for uremic patients and patients are treated with 1,25-dihydroxyvitamin D3. The bone scanning agent 99mTc-phosphate has also been used to evaluate in ROD but it is not clear that bone scintigraphy has a role in the follow-up of treatment. In this study 99mTc(V)-DMSA scintigraphy was performed in eleven patients [age 40.7 +/- 17.3 (...

Introduction: Medullary thyroid carcinoma (MTC) is a rare thyroid cancer secreting calcitonin (CT) which is the most sensitive and specific tumor marker for MTC. This type of thyroid cancer is able to metastasize to different body areas including regional lymph nodes, lungs, liver and bone. The aim of this study was to assess the sensitivity and specificity of [99mTc-DMSA (V)] whole body ...

introduction due to limitation of colonoscopy in assessing the entire bowel and patients’ intolerance in inflammatory bowel disease (ibd), in the current study, we aimed to prospectively compare the accuracy of 99m tc(v)-dimercaptosuccinic acid (dmsa) and fecal calprotectin with ileocolonoscopy as new methods for localizing inflammations. methods current prospective study conducted between 2012...

Introduction: Medullary thyroid carcinoma (MTC) is a rare thyroid cancer secreting calcitonin (CT) which is the most sensitive and specific tumor marker for MTC. This type of thyroid cancer is able to metastasize to different body areas including regional lymph nodes, lungs, liver and bone. The aim of this study was to assess the sensitivity and specificity of [Tc-DMSA (V)] whole body scan (WBS...

OBJECTIVE The objective of this study was to investigate arsenic induced changes in blood delta-aminolevulinic acid dehydratase (ALAD) after in vitro and in vivo exposure to this element and its response to co-administration of meso 2,3-dimercaptosuccinic acid (DMSA) and monoisoamyl DMSA (MiADMSA) either individually or in combination. METHODS Rat whole blood was exposed to varying concentrat...

PURPOSE To determine prevalence and risk factors for renal scar in children referred for urologic assessment of febrile UTI and/or VUR. METHODS Pre-determined risk factors for renal scar were prospectively recorded in consecutive patients referred for UTI/VUR. Age, gender, VUR grade, and reported number of febrile and non-febrile UTIs were analyzed with logistic regression to determine risk f...