Stimulation of chromaffin cells in culture with 1,1-dimethyl-4-phenylpiperazinium (DMPP) or depolarizing concentrations of K+ resulted in a significant secretion of high and low molecular weight enkephalin-like peptides (ELPs) into the culture medium. BioGel P-10 column chromatography was used to characterize the ELPs in chromaffin cell extracts and in culture media before and after stimulation...

Nitrogen (N) losses through nitrate leaching, occurring after slurry spreading, can be reduced by the use of nitrification inhibitors (NIs) such as dicyandiamide (DCD) and 3,4-dimethyl pyrazole phosphate (DMPP). In the present work, the effects of DCD and DMPP, applied at two rates with cattle slurry, on soil mineral N profiles, annual ryegrass yield, and N uptake were compared under similar pe...

The presence of local ganglion-like receptors in the anterior segment of the cat eye was demonstrated in an isolated, arterially perfused preparation. The administration of the known ganglionic stimulants, acetylcholine (Ach) plus eserine, pilocarpine, and dimethylphenylpiperazinium bromide (DMPP) produced a vasconstriction. The actions of these stimulants were abolished by a-adrenergic blockad...

During postembryonic stages, metazoans synchronize the development of a large number of cells, tissues and organs by mechanisms that remain largely unknown. In Caenorhabditis elegans larvae, an invariant cell lineage is tightly coordinated with four successive molts, thus defining a genetically tractable system to analyze the mechanisms underlying developmental synchronization. Illegitimate act...

佐久間 昭 * Present Address : Department of Pharmacology , Institute for Cardiovascular Diseases, Tokyo Medi cal & Dental University, Bunkyu-ku, Tokyo. Ftc. 1. In autoperfusion of dog hindquarters, distal electro stimulation (E) of the divided lumbar sympathetic chains and i.a. DMPP (D) are serially challenged by fl-TM 10, tripelennamine (PBZ) and atropine (Atr). Intraarterial injection of 20 to 10...

The application of nitrification inhibitors (NIs) is considered to be an efficient way delay nitrification, but the effect NIs combinations on soil and ammonia (NH3) volatilization are not clear in soils with different pH values. In this study, we explored nitrapyrin (CP) its 3, 4-dimethylepyrazole phosphate (DMPP), dicyandiamide (DCD) transformation nitrogen, potential rate (PNR), a 120-day in...

Nitrogen loss after urea application and the low nitrogen utilization rate of plants are major issues in fertilizer application. We therefore adopted a combination 3,4-dimethylpyrazole phosphate (DMPP) applications order to investigate response DMPP ‘sweet sapphire’ (V. vinifera L.) grape seedlings growth. Three combinations were tested screen suitable concentrations for seedlings’ Transcriptom...

The effects of nitrification inhibitor in tea gardens with different urea–N rates have rarely been assessed. For eight months, a glasshouse experiment was conducted to investigate the (3, 4–dimethylpyrazole phosphate, DMPP) on changes soil pH and inorganic N loss. Urea (0, 300, 500, 800 kg ha−1) or without DMPP (1% applied) were added pots that hosted six plants three years old. Next, leaching ...

HAAS and Goldblatt 1 reported that infusion of DMPP (l,l-dimethyl~t-phenylpiperazinium iodide), a ganglion stimulating agent, causes increase of pressor responsiveness to angiotensin. The experiments reported here reveal that, instead of enhancement of the direct effect of angiotensin on the cardiovascular S3'Stem, the larger responses that follow treatment with DMPP are due to adrenal discharg...