The tensin family member cten (C-terminal tensin like) is an Src homology 2 (SH2) and phosphotyrosine binding domain-containing focal adhesion molecule that may function as a tumor suppressor. However, the mechanism has not been well established. We report that cten binds to another tumor suppressor, deleted in liver cancer 1 (DLC-1), and the SH2 domain of cten is responsible for the interactio...

In our previous study we demonstrated the downregulation or loss of deleted in liver cancer‑1 (DLC-1) gene expression in nasopharyngeal carcinoma (NPC). In this study, we report the effects of the DLC-1 gene on NPC cells and its mechanisms of action. DLC-1 expression was restored in the 5-8F NPC cell line, which lacks DLC-1 expression, and the biological characteristics of 5-8F-DLC‑1 cells were...

Diamond like carbon (DLC) films were deposited on Si and then patterned to form 40 nm features as nanoimprint templates. A plasma enhanced chemical vapor deposition (PECVD) system with CH4 precursor was used to deposit DLC films on Si and quartz substrates. These films were then characterized using Raman spectroscopy, atomic force microscopy (AFM), nanoindentation, and contact angle measurement...

Ultra-thin diamond-like carbon (DLC) coatings are used in hard disk drives to protect the intricate magnetic structures from wear and corrosion. The coating on the recording head consists of a hard DLC layer and a silicon (Si) layer that improves adhesion between the DLC layer and the substrate. Damage to this protective coating can expose the magnetic structures to corrosion and compromise the...

The clustering of glycine receptors and major subtypes of GABA(A) receptors at inhibitory synapses is mediated by the tubulin-binding protein gephyrin. In an attempt to identify additional components of inhibitory postsynaptic specializations, we performed a yeast two-hybrid screen using gephyrin as bait. Multiple positive clones encoded either the dynein light chain-1 (Dlc-1), also known as dy...

The interaction between resist and template during the separation process after nanoimprint lithography (NIL) can cause the formation of defects and damage to the templates and resist patterns. To alleviate these problems, fluorinated self-assembled monolayers (F-SAMs, i.e. tridecafluoro-1,1,2,2,tetrahydrooctyl trichlorosilane or FDTS) have been employed as template release coatings. However, w...

The biological response of human microvascular endothelial cells (HMEC-1) seeded on Si-DLC films and on control surfaces was evaluated in terms of initial cell enhancement, growth, and cytotoxicity. The microstructure of the films was characterised by Raman spectroscopy and X-ray photoelectron spectroscopy. The effect of changes in microstructure, surface energy, surface electronic state, and e...

Poly aryl-ether-ether-ketone (PEEK) is an alternative to metal alloys in orthopedic applications. Although the polymer provides many significant advantages such as excellent mechanical properties and non-toxicity, it suffers from insufficient elasticity and biocompatibility. Since the elastic modulus of diamond-like carbon (DLC) is closer to that of cortical bone than PEEK, the DLC/PEEK combina...

this paper proposes an optimal power flow (opf) algorithm by direct load control (dlc) programs to optimize the operational cost of smart grids considering various scenarios based on different constraints. the cost function includes active power production cost of available power sources and a novel flexible load curtailment cost associated with dlc programs. the load curtailment cost is based ...

Co-depositing of nickel (Ni) and nitrogen (N2) in the diamond-like carbon (DLC) matrix was synthesized by pulsed laser deposition (PLD) technique. In work presented here, N2 injected as a reactive gas to optimize optical, structural properties Ni:N-DLC thin films, although argon (Ar) ratio kept constant. Statistical films were calculated from surface topographic images 2Ni:N-DLC, 3Ni:N-DLC, 4Ni...