Eight patients with chronic open-angle glaucoma who had an intraocular pressure greater than 24 mm Hg at some time during the day while taking timolol 0.5% twice daily were given the fixed ratio combination of timolol 0.5% with pilocarpine 2% (TP2) twice daily. By comparing full 24-hour diurnal curves on timolol with those on TP2 it was possible to show that all patients except one (at a single...

PURPOSE To investigate diurnal intraocular pressure (IOP) fluctuation in eyes with angle-closure. MATERIALS AND METHODS Seventy-seven eyes of 77 newly diagnosed patients with angle closure [33 subjects with primary angle-closure suspects (PACS), 23 subjects with primary angle-closure (PAC), and 21 subjects with primary angle-closure glau-coma (PACG)] were enrolled after laser peripheral irido...

PURPOSE To investigate the diurnal variation in axial length and anterior eye biometrics, while simultaneously measuring intraocular pressure (IOP) with dynamic contour tonometry in human subjects. METHODS Fifteen young adult near-emmetropic subjects had axial length, anterior eye biometrics (central corneal thickness and anterior chamber dimensions), and IOP measured at six different times a...

PURPOSE To describe the 1-year success of a trabecular stent implant in a pseudophakic glaucoma patient. The stent is implanted through a small corneal incision under gonioscopic control. Intraocular pressure control was reported in cultured human anterior segment. DESIGN Observational case report. METHODS We report the case of a patient who was implanted and followed-up for 1 year at the D...

PURPOSE We studied the relationship between nocturnal habitual position IOP elevation and diurnal IOP level in normal-tension glaucoma (NTG) patients. METHODS A total of 70 young NTG patients with a low diurnal IOP level (mean diurnal seated IOP < 15.0 mm Hg; low IOP group) and 79 age-, axial length-, and disease severity-matched NTG patients with a high diurnal IOP level (mean diurnal seated...