abstract         background and objective: one of the main tasks of clinical microbiology laboratories is to determine antibiotic resistance profiles in common pathogens and ensure the selection of effective antibiotics for certain infections. the aim of this study was to compare the methods of disk diffusion, broth microdilution and modified hodge test in escherichia coli isolates from urinary...

background: leishmaniases are a group of diseases caused by leishmania parasites .  growing of drug unresponsiveness in leishmaniasis patients necessitates the development of new drugs and accor­dingly a suitable assay is needed for evaluation of any modalities.  the aim of this study was to compare four drug assays methods, agar dilution, broth dilution, cylinder plate and disk diffusion, for ...

Abstract In the present study, nanoparticles of copper and copper oxides were synthesized and their antibacterial activity was evaluated and compared with silver nanoparticles. The nanoparticles were synthesized using facile chemical reactions, and then characterized using field emission scanning microscopy. The nanoparticles were stable for at least two weeks. The...

background. this study evaluated the antimicrobial activity of tetraacetylethylenediamine-sodium perborate (taed-sp) in comparison to 2.5% and 5% sodium hypochlorite (naocl) against enterococcus faecalis. methods. a standard suspension of e. faecalis was inoculated on 60 plates containing mueller-hinton agar culture medium. four sterile disks of beckman filtration paper were placed on each plat...

tigecycline is a new glycylcycline antibiotic structurally similar to minocycline antibiotic. it has broad spectrum activity, including staphylococcus aureus infections. this is the first study that evaluated the activity of tigecycline against staphylococcus aureus isolated from biological samples in iran. in vitro activity of tigecycline against 160 staphylococcus aureus including 99 methicil...

background and aims: escherichia coli are one of the important causes of diarrhea in children, adult and immune compromised ones in developing country. the aim of this study was to investigate the antibiotic resistance of e. coli isolated from gastroenteritis cases in shahrekord county, in order to obtain a rapid and suitable treatment. methods: in this descriptive analytical study, 234 fecal s...

 Methicillin resistant Staphylococcus aureus (MRSA) has been emerged as a nosocomial and community acquired pathogen worldwide. There are many challenges for laboratory detection of MRSA. The aim of this study was to compare different phenotypic methods with PCR based method as a gold standard for detection of mecA gene to detection of MRSA. A total of 220 clinical isolates of S. aureus which w...

A new 16-membered macrolide named makinolide B (1) was isolated from Streptomyces sp. MK-19. The structure of makinolide B (1) was determined on the basis of 2D NMR experiments involving DQF-COSY, TOCSY, HSQC, and HMBC methods. Application of the paper disk diffusion method to makinolide B (1) showed weak antibacterial activity against Staphylococcus aureus at the dose of 100 µg/disk.

BACKGROUND Staphylococcus saprophyticus is the second most frequent community-acquired causative agent of urinary tract infection (UTI). The objective of this study was to evaluate the susceptibility profile and resistance detection in Staphylococcus species. isolated from patients with UTI. MATERIALS AND METHODS The isolates were investigated using the disk diffusion method, Vitek I system, ...