Background:The incidence rate of head and neck cancer in the world is about 560,000 new cases a year. Larynx cancer is the most common malignancy in head and neck in Iran. The most common head and neck carcinoma is the malignancy of squamous epithelial cells. This study was conducted to determine the survival rate of patients undergoing nonsurgical treatment methods for larynge...

background: the aim of this study was to investigate the efficacy and safety of metronomic capecitabine chemotherapy in pretreated elderly patients with advanced gastric carsonoma. patients and methods: eligible patients were treated with capecitabine at a fixed dose of 1000mg daily until disease progression or toxicity. endpoints were overall response rate, safety, progression-free survival an...

gaucher disease (gd) is the most common type of lysosomal storage disorder and it is divided into three distinct subtypes. the authors here report four different cases of gaucher disease, with varying clinical manifestations, and the diagnosis of each established by the low level of beta-glucosidase enzyme as well as genetic dna testing. the study also highlights the importance of early diagnos...

Background: The aim of this study was to investigate the efficacy and safety of metronomic capecitabine chemotherapy in pretreated elderly patients with advanced gastric carsonoma. Patients and Methods: Eligible patients were treated with capecitabine at a fixed dose of 1000mg daily until disease progression or toxicity. Endpoints were overall response rate, safety, progression-free survival...

results like other cancers, prostate cancer is caused by an accumulation of genetic alterations in a cell that drives it to malignant growth. specific genes and gene alterations have been suggested to play a role in its development and progression. aneuploidy, loss of heterozygosity, gene mutations, hypermethylation and inactivation of specific tumour suppressor genes such as gstpi, apc, mdr1, ...