We describe a patient with discoid lupus erythematosus whose pattern of disease evolved into a systemic vasculitis polyarteritis nodosa.

Lupus erythematosus panniculitis or lupus erythematosus profundus is characterized by inflammation of the deep dermis and subcutaneous tissue. It can occur in isolation or associated with chronic systemic or discoid lupus erythematosus. It usually consists of nodules and hardened subcutaneous plaques on the forehead, cheeks, proximal extremities, and buttocks. Periorbital and parotid involvemen...

Although thalidomide is a U.S. Food and Drug Admistration (FDA) approved medication for erythema nodosum leprosum and multiple myeloma, it has many off-label uses, including for discoid lupus erythematosus (DLE), Behçet's disease, apththous ulcers in HIV patients, and prurigo nodularis. Herein, we present a patient with an overlap of discoid lupus erythematosus and lichen planus who was success...

ANA: antinuclear antibody BID: twice a day CLE: cutaneous lupus erythematosus DIL: drug-induced lupus SLE: systemic lupus erythematosus INTRODUCTION Cutaneous lupus erythematosus (CLE), defined as isolated cutaneous lesions without significant systemic involvement, has a reported incidence and prevalence of 4.3 and 73.2 per 100,000, respectively. It occurs more commonly among women with a repor...

Because of the frequent presence of polyarthritis and the rheumatoid factor in cases of systemic lupus erythematosus (S.L.E.) and that of the L.E.-cell phenomenon and visceral lesions in cases of rheumatoid arthritis, it was thought that it would be profitable to study the correlation between the two diseases. The disseniination of discoid lupus erythematosus, especially after exposure to stron...

Scalp involvement with hair loss is common in systemic lupus erythematosus. Discoid erythematosus may cause scarring alopecia, characterized by well-delimited erythematous plaques scales, follicular hyperkeratosis and atrophy, which considered a trichological emergency. Early diagnosis treatment are necessary order to prevent permanent loss. We describe 44 years’ old female patient for 4 years,...

Neonatal lupus erythematosus is a very rare disease, clinically characterized by skin lesions that resemble those of subacute or discoid lupus erythematosus and/or congenital heart block. Generally, when patients have skin manifestations, they have no cardiac defects and vice-versa; however, in 10% of cases these manifestations may coexist. Other findings may include hematologic, hepatic and ne...