Preservation of the meniscus has been shown to influence the progression of degenerative changes of the knee. As more meniscus is preserved, the propensity for development of osteoarthritis is lessened. Surgical treatment of a torn discoid meniscus has typically been a subtotal meniscectomy or partial meniscectomy. Similar to tears of a normal meniscus, partial meniscectomy compared with subtot...

INTRODUCTION Discoid lupus erythematosus may lead to significant orbital inflammation syndrome. Ocular manifestations related to discoid lupus erythematosus are uncommon and few cases of eye inflammation are reported. CASE PRESENTATION A 37-year-old Caucasian woman with 5-year history of discoid lupus erythematosus presented with exophthalmos, periorbital pain and blurred vision in her right ...

Immune response to ultraviolet radiation-modified skin antigens has been suggested as a pathomechanism of skin lesions in discoid lupus erythematosus and polymorphous light eruption. In order to elucidate the role of T-lymphocyte subsets in this response, we studied the distribution of CD45RO+, CD45RA+ and CD31+ cells and the endothelial expression of adhesion molecules E-selectin/P-selectin, i...

Meniscal tears and meniscal instability are rare complications of a discoid lateral meniscus in a very young child. We report a case of a 32-month-old male who presented with a limp and limited extension of his right knee. Magnetic resonance and sonographic images demonstrated a discoid meniscus with a posterior horn tear and unstable anterior horn, confirmed by arthroscopy. The patient was tre...

INTRODUCTION A discoid medial meniscus is a rare pathology of the knee joint, and is even rarer when it presents bilaterally with clinical symptoms. CASE PRESENTATION We present the case of a 38-year-old female with symptomatic bilateral discoid medial meniscus. Magnetic Resonance Imaging (MRI) showed complete discoid meniscus in one knee and incomplete, on the other side. The MRI findings we...

The discoid meniscus is probably a congenital deviation that usually occurs laterally. The Watanabe classification consists of complete, incomplete, or Wrisburg ligament types. Complete and incomplete discoid menisci normally require treatment only when a tear occurs. The Wrisburg ligament type lacks a posterior capsular attachment. The preferred treatment is repair of the posterior capsular di...

Thromb Haemost 2007; 98: 73–76 Ernst F. Lüscher had posed some interesting questions in 2000 about the time flow of the first platelet reactions after activation: shape change (SC) or aggregation (1). Regarding in-vivo studies – commencing on the observations of Bizzozero in 1882 (2) – Lüscher deduced from the literature and from own investigations (3, 4) that shape change which precedes aggreg...

INTRODUCTION Discoid meniscus is an atavistic anomaly in which the meniscus of the knee, predominantly the lateral meniscus, is discoid rather than semilunar in shape. The abnormality is diagnosed relatively infrequently and may even go unrecognized or be untreated. Treatment has consisted of either partial or complete meniscectomy performed either arthroscopically or by open arthrotomy. Our pu...

OBJECTIVE Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterised by heterogeneous clinical manifestations, autoantibody production and epigenetic dysregulation in T cells. We sought to investigate the epigenetic contribution to the development of cutaneous manifestations in SLE. METHODS We performed genome-wide DNA methylation analyses in patients with SLE stratified...

A ring-shaped lateral meniscus is an uncommon morphological variant, and its etiology remains unclear. A 38-year-old male was admitted to our institution complaining of right knee pain and locking. Magnetic resonance imaging suggested a bucket-handle tear in the medial meniscus and a discoid lateral meniscus. On arthroscopic evaluation, however, a ring-shaped lateral meniscus was detected in th...