Due to special conditions of Iran; i.e., neighboring to major centers of drug production in Afghanistan during the last few decades, it was the passageway of the drug to Europe. Moreover, because of appropriate context of social, economic and cultural situations, there was an increased addiction and drug trafficking in Iran. It is obvious that a lot of people would be involved directly and indi...

SUMMARY Three cases ofauto-immune addison's disease are reported in association with hyperprolactilinemia. All of them had galactorrhea. In three cases complete resolution of hyperprolactitinemia occurred with corticosteroid replacement. We suggest that hyperprolactinemia was due to cortisol deficiency operating directly or indirectly at the level of the pituitary.  

While epidemiological studies have suggested that aluminum is a risk factor for Alzheimer disease (AD), the underlying mechanism through which aluminum leads to AD remains unknown. Despite the lack of evidence linking aluminum to AD that have motivated many to avoid using materials such as cooking utensils made with the metal, researchers have yet to investigate the precise effects of aluminum ...

various stresses during life can affect metabolism and brain activities, immune and endocrine systems directly and indirectly, and ultimately, causes animal behavior change. the cellular and molecular level change in neurotransmitter and hormone concentrations led to the functional changes of operating systems in the intracellular organelles.  these events cause of course oxidative stress. all ...

Adoptive transfer of regulatory T cells (Tregs) prevents GVHD in experimental animals. Because antigen activation drives Treg function, we measured the frequency, growth requirements, and function of alloantigen-specific (allospecific) Tregs from human blood. When alloantigen was presented directly, the precursor frequency of allo-specific Tregs in normal individuals was 1.02% (95% confidence i...

brucella melitensis and brucella abortus are of the most important causes of brucellosis, an infectious disease which is transmitted either directly or indirectly including consuming unpasteurized dairy products. both strains are considered endemic in iran. common diagnostic methods such as bacteriologic cultures are difficult and time consuming regarding the bacteria. the aim of this study was...