DNA damage-inducible (din) genes in Bacillus subtilis are coordinately regulated and together compose a global regulatory network that has been termed the SOS-like or SOB regulon. To elucidate the mechanisms of SOB regulation, operator/promoter regions from three din loci (dinA, dinB, and dinC) of B. subtilis were cloned. Operon fusions constructed with these cloned din promoter regions rendere...

This paper will report on lessons learned from two studies using blended learning courses involving past and present experience of the authors. Will also discuss the importance of online asynchronous discussions in the teaching and learning process. The paper concludes with suggested guidelines for the use of asynchronous online discussions, considered useful for instructors who teach for the f...

We have identified many dark-inducible (din) genes that are expressed in Arabidopsis leaves kept in the dark. In the present study we addressed the question of how plant cells sense the depletion of sugars, and how sugar starvation triggers din gene expression in suspension-cultured cells of Arabidopsis. Depletion of sucrose in the medium triggered marked accumulation of din transcripts. Suppre...

Irrigated agriculture can modify the cycling and transport of nitrogen (N), due to associated water diversions, water losses, and changes in transport flow-paths. We investigate dominant processes behind observed long-term changes in dissolved inorganic nitrogen (DIN) concentrations and loads of the extensive (465,000 km2) semi-arid Amu Darya River basin (ADRB) in Central Asia. We specifically ...

Transformatoarele de putere de înaltă tensiune reprezintă unele din cele mai costisitoare echipamente din staţiile electrice din sistemul electroenergetic. Defectele şi opririle accidentale ale acestora nu cauzează numai costuri cu reparaţiile; ele conduc şi la pierderi ecomonice datorate întreruperii alimentării consumatorilor. Testele preventive şi monitorizarea on-line sunt benefice pentru p...

The pronounced increase in the cycling and deposition of biologically reactive dissolved inorganic nitrogen (DIN) over large areas globally not only cause increased concentrations of DIN in surface waters, but it will also affect nutrient ratios in rivers, lakes and coastal areas. This review addresses the flux and fate of DIN, focusing NO3 in lakes of boreal and alpine catchments. Not only DIN...

Receiving coastal waters and estuaries are among the most nutrient-enriched environments on earth, and one of the symptoms of the resulting eutrophication is the proliferation of opportunistic, fast-growing marine seaweeds. Here, we used a widespread macroalga often involved in blooms, Ulva spp., to investigate how supply of nitrogen (N) and phosphorus (P), the two main potential growth-limitin...

Given H a real Hilbert space and Φ : H → R a smooth C function, we study the dynamical system (DIN) ẍ(t) + αẋ(t) + β∇Φ(x(t))ẋ(t) +∇Φ(x(t)) = 0 where α and β are positive parameters. The inertial term ẍ(t) acts as a singular perturbation and, in fact, regularization of the possibly degenerate classical Newton continuous dynamical system ∇Φ(x(t))ẋ(t)+∇Φ(x(t)) = 0. We show that (DIN) is a well-pos...

In aquatic ecosystems, carbon (C) availability strongly influences nitrogen (N) dynamics. One manifestation of this linkage is the importance in the dissolved organic matter (DOM) pool of dissolved organic nitrogen (DON), which can serve as both a C and an N source, yet our knowledge of how specific properties of DOM influence N dynamics are limited. To empirically examine the impact of labile ...

BACKGROUND Postsurgical treatment of ductal intraepithelial neoplasia (DIN) with standard doses of tamoxifen has not reached a consensus yet. Given positive results of low-dose tamoxifen on breast cancer biomarkers modulation, we analyzed a large cohort of DIN patients treated with low-dose tamoxifen or no treatment as per institutional guidelines. PATIENTS AND METHODS All consecutive women o...