INTRODUCTION Xanthoma (or xanthofibroma) is a benign proliferative lesion, mostly seen in soft tissue. Xanthoma of bone is very rare benign primary bone tumor, more frequently seen in men and in patients over 20 years of age. Histologically, it is characterized by mononuclear macrophage-like cells, abundant foam cells, and multinucleated giant cells. It is sometimes discovered coincidentally an...

We present a 42-year-old man with a 1-month history of painless jaundice, dark urine, clay-colored stools, and a 13.5-kg weight loss. Laboratory tests revealed elevated liver enzymes and CA19-9. Imaging showed dilation of both the intra- and extrahepatic bile ducts, narrowing of the bile duct at the junction of the common bile duct and common hepatic duct, and a hypoechoic mass involving the ne...

Esophageal xanthoma is a rare lesion which is an asymptomatic small yellowish polyp, and most of the reported cases were solitary lesion. Histologically, aggregations of foam cells are found under the papillary hypertrophic squamous epithelium and the foam cells express CD68. The etiology of esophageal xanthoma is unknown. The focal irritation of the esophageal mucosa and infiltrated inflammato...

BACKGROUND Xanthoma disseminatum is a rare nonfamilial disease characterized by lipid deposition in skin and internal organs due to histiocytic cell proliferation, classified as a benign non-Langerhans cell histiocytosis. This chronic disease has no known established treatment. We report 8 cases of xanthoma disseminatum with treatment outcomes in long-term follow-up and provide a review of the ...

Xanthogranulomatous pyelonephritis (XGP) is a chronic inflammatory process that results in replacement of renal and/or perirenal tissue with a diffuse infiltrate of inflammatory cells referred to as xanthoma cells. We present a case of a 49-year-old man with an incidentally discovered renal mass with inferior vena cava (IVC) thrombus, who was found intraoperatively to have a significant inflamm...

Xanthoma of bone is a rare disorder which occurs due to cholesterol deposits in the bone. Clinically patients usually present with pain or fracture affected Radiologically it presents as lytic lesion, often cortical expansion disruption. associated hyperlipidemia but cases non- xanthoma are also reported, termed primary xanthoma. Here we case 46-year-old male who presented and swelling right mi...

Bone xanthoma is a rare benign primary bone lesion histologically characterized by sheets of foamy cells which are macrophages with cytoplasm filled droplets fat. It usually associated endocrine or metabolic diseases, in the absence called xanthoma. Because lack pathognomonic radiologic and clinical features, they require differential diagnosis broad spectrum lesions varying degree malignant po...

Verruciform xanthoma is a benign, soft tissue lesion occurring on the orogenital mucosa. Presentation of oral lesions can be pink, yellow, or gray raised plaque or papule with granular, papillary, or verrucous in nature. There are many theories proposed for the etiopathogenesis of verruciform xanthoma. Clinical observations may be misguiding as the lesion resembles malignant and premalignant le...

We are reporting a case of a 12-year-old girl with xanthoma, as a very rare presentation of new onset type one diabetes in children. Xanthoma is a papular skin rash that is associated with severe hypertriglyceridemia, in our patient this was secondary to undiagnosed type one diabetes mellitus. The rash was misdiagnosed as viral illness, till she presented one month later with diabetic ketoacido...