Artemisinin (ART) is a sesquiterpene lactone and popular malaria drug used in many parts of the world. Artesunate (ARTS) semi-synthetic derivative ART with improved pharmacokinetic properties. However, half-life ARTS less than an hour vivo. The analysis this vitro different solvent systems using LC-MS/TOF showed solvent-driven breakdown. breakdown formed several derivatives, including dihydroar...