نتایج جستجو برای: dietzia natronolimnaea hs1
تعداد نتایج: 394 فیلتر نتایج به سال:
The 75-kD HS1 protein is highly tyrosine-phosphorylated during B cell antigen receptor (BCR)-mediated signaling. Owing to low expression of HS1, WEHI-231-derived M1 cells, unlike the parental cells, are insensitive to BCR-mediated apoptosis. Here, we show that BCR-associated tyrosine kinases Lyn and Syk synergistically phosphorylate HS1, and that Tyr-378 and Tyr-397 of HS1 are the critical resi...
In B-Chronic Lymphocytic Leukemia (B-CLL) kinase Lyn is overexpressed, active, abnormally distributed, and part of a cytosolic complex involving hematopoietic lineage cell-specific protein 1 (HS1). These aberrant properties of Lyn could partially explain leukemic cells' defective apoptosis, directly or through its substrates, for example, HS1 that has been associated to apoptosis in different c...
Numerous aspects of T cell function, including TCR signaling, migration, and execution of effector functions, depend on the actin cytoskeleton. Cytoskeletal rearrangements are driven by the action of actin-regulatory proteins, which promote or antagonize the assembly of actin filaments in response to external cues. In this work, we have examined the regulation and function of HS1, a poorly-unde...
Natural Killer (NK) cells perform many functions that depend on actin assembly, including adhesion, chemotaxis, lytic synapse assembly and cytolysis. HS1, the hematopoietic homolog of cortactin, binds to Arp2/3 complex and promotes actin assembly by helping to form and stabilize actin filament branches. We investigated the role of HS1 in transendothelial migration (TEM) by NK cells. Depletion o...
استفاده از رنگی که علاوه بر دارا بودن خصوصیات رنگی مشابه رنگهای مصنوعی ، دارای فوائد به اثبات رسیده در برخی از فراورده های غذایی نظیر روغن باشد، یک ضرورت است. از طرفی این رنگها می بایست فاقد مضرات رنگهای مصنوعی باشند. در این خصوص رنگ کانتاگزانتین بدلیل خاصیت رنگ دهی مشابه رنگ های مصنوعی و نداشتن مضرات آنها به عنوان یک رنگ کاملاً طبیعی برای استفاده در روغن های خوراکی ، گزینه مطلوبی به نظرمی رسد. ...
Here, we report the draft genome sequence of Dietzia maris, known previously as Rhodococcus maris It is 3,505,372 bp in size with a G+C content of 73%. The draft genome sequence will improve our understanding of Dietzia maris related to other mycolata species and constitutes a basic tool for exploring the cell wall proteins.
The newly isolated strain E1, identified as a Dietzia sp., proved to have an excellent ability to degrade n-C12 to n-C38 alkane components of crude oil. The preferred substrate was the very long-chain alkane n-eicosane at an optimal temperature of 37 degrees C and an optimal pH of 8 under aerobic conditions. The growth and substrate uptake kinetics were monitored during the n-alkane fermentatio...
The actin regulatory protein HS1 is required for antigen uptake and presentation by dendritic cells.
The hematopoietic actin regulatory protein hematopoietic lineage cell-specific protein 1 (HS1) is required for cell spreading and signaling in lymphocytes, but the scope of HS1 function in Ag presentation has not been addressed. We show that dendritic cells (DCs) from HS1(-/-) mice differentiate normally and display normal LPS-induced upregulation of surface markers and cytokines. Consistent wi...
Collagen activates platelets through an intracellular signaling cascade downstream of glycoprotein VI (GPVI). We have investigated the contribution of hematopoietic lineage cell-specific protein 1 (HS1) downstream of GPVI in platelet activation. Stimulation of GPVI leads to tyrosine phosphorylation of HS1, which is blocked by Src-family kinase inhibitors. Coimmunoprecipitation experiments revea...
Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland Figure 1 Performance of the tailored pulses. a) Example characteristics of the HS1-derived TR-FOCI pulse. Note that the optimized pulse is broad compared to the standard HS1 (dotted line). b) Slice-excitation profile of the same HS1-derived TR-FOCI pulse. Above a low pulse power of gB1≈200 Hz, the pro...
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