anopheles culicifacies is the vector of malaria in southeastern part of iran, india, west pakistan and ceylon. in 1959 the lc50 % ddt in the panchmahal district of gujarat state (india) had increased. ddt resistant population of a. culicifacies has been reported from west pakistan, burma and iran. after application of ddt in 1959, the density of a. culicifacies decreased sharply. the susceptibi...

The estrogenic activity of dieldrin, toxaphene, and an equimolar mixture of both compounds (dieldrin/toxaphene) was investigated in the 21-day-old B6C3F1 mouse uterus, MCF-7 human breast cancer cells, and in yeast-based reporter gene assays. Treatment of the animals with 17beta-estradiol (E2) (0.0053 kg/day x3) resulted in a 3.1-, 4.8-, and 7.8-fold increase in uterine wet weight, peroxidase ac...

WIESE, I. H., BASSON, N.C.] ., BASSON, P. A., NAUDE, T. W. & MAAR TENS, B. P., 1972. The toxicology and pathology of dieldrin and photodieldrin poisoning in two antelope species. Onderstepoort f. vet. Res. 40(1), 31-40 (1973) Blesbuck (Damalisms dorcas phil!tpsi) and springbuck (Antidorcas marsupia/is) were found to be more susceptible to dieldrin and its photoisomer than any. vertebrates repor...

The current study was undertaken to investigate the dose-response characteristics of dieldrin-mediated enhancement of liver tumour formation in CF-1 mice. The median time to tumour development was established in controls, and in dieldrin-treated animals at six levels of continuous exposure (0.1, 1, 2.5, 5, 10 and 20 p.p.m.). The results of the analysis, which was based on liver tumour data from...

・・・・・Carbaryl was well absorbed from the small intestine of rats. In the cytosol fraction of intestinal mucosa, it was bound to a smallmolecular component (M. W. 2,200 daltons). In serum, carbaryl was bound mainly to albumin and partly te globulins. Dieldrin was slowly absorbed from small intestine. The peak of dieldrin concentration in blood was observed 2.5 hr after the administration. Bindin...

The effects of ethanol alone or ethanol and dieldrin given orally were investigated on the reproductive processes of female Long-Evans rots. Three studies were undertaken: effects on reproduction (phose 1), perinatal and postnatal effects {phase Ill}, and teratological effects (phose II}. Female Long-Evans rats were divided into five groups for all studies: group /-distilled water; group //-cor...

In the present study, changes in velocity of cytoplasmic streaming in the giant internodal cells of Nitella for varying concentration of the pesticides, 2,4-D, dieldrin, malathion, methyl parathion and endosulfan, were measured. Marked decrease in the velocity of cytoplasmic streaming was found at the concentrations of 0.01, 0.1, 1, 10 and 100mM. Dieldrin was the most toxic to all the pesticide...

The chemical degradation of dieldrin in ferric sulfide and iron powder aqueous suspension was investigated in laboratory batch type experiments. To identify the reaction mechanism, reduced copper was used as reductant. More than 90% of dieldrin was degraded using both reaction systems after 29 days. Initial degradation rate of the pesticide using ferric sulfide was superior to that using iron p...

BACKGROUND Declining human reproductive health over the last 60 years has been proposed to be due to effects of environmental chemicals, especially endocrine disrupting compounds, on fetal development. We investigated whether a model pesticide, dieldrin, at concentrations within both maternal circulation and environmental ranges (1 pmol/l = 0.0004 p.p.b. = 380.9 pg/l), could disrupt the human f...

Introduction The established and large-scale use of certain synthetic chemicals, especially pesticides, has led to their absorption and deposition in animals and man. The authors' interest lay in the pharmacodynamics of the synthetic organochlorine insecticide, dieldrin, which is primarily deposited and stored in the body lipid. Its study required repeated measurements of the deposition of this...