نتایج جستجو برای: didmoad

تعداد نتایج: 60  

2016
Mami Fukuma Daisuke Ariyasu Megumi Hatano Hiroko Yagi Yukihiro Hasegawa

Wolfram syndrome (WS) is an autosomal recessive neurodegenerative disorder characterized by DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy, and deafness). Genetic analysis has demonstrated mutations of the WOLFRAMIN gene (WFS1) in patients with this syndrome (1), which may be complicated by other conditions, among them urological disorders (UDs). According to one study, UDs were ...

Journal: :AJNR. American journal of neuroradiology 2007
S Ito R Sakakibara T Hattori

Wolfram syndrome is a rare autosomal recessive disorder featuring diabetes insipidus, diabetes mellitus, optic atrophy, and deafness; DIDMOAD is a commonly accepted anonym for this disorder. We describe a 35-year-old man with Wolfram syndrome, who had marked atrophy of the brain stem, middle cerebellar peduncle, and cerebellum. Despite these MR imaging findings involving the pontocerebellar tra...

ATAOLLAH BEHROUZ AGHDAM, DAVOOD SHARIFI DOLOUI,

Two brothers with DIDMOAD syndrome are reported. The older brother has diabetes mellitus (type I), diabetes insipidus, optic atrophy, deafness and atonia of the urinary tract with severe symptoms such as diabetic ketoacidosis and frequent urinary tract infections. His younger brother had the same manifestations but with less severity. We report the findings of our two patients and compare ...

Journal: :medical journal of islamic republic of iran 0
davood sharifi doloui university of medical sciences, mashhad, islamic republic of iran ataollah behrouz aghdam

two brothers with didmoad syndrome are reported. the older brother has diabetes mellitus (type i), diabetes insipidus, optic atrophy, deafness and atonia of the urinary tract with severe symptoms such as diabetic ketoacidosis and frequent urinary tract infections. his younger brother had the same manifestations but with less severity. we report the findings of our two patients and compare them ...

2014
Kimie Matsunaga Katsuya Tanabe Hiroshi Inoue Shigeru Okuya Yasuharu Ohta Masaru Akiyama Akihiko Taguchi Yukari Kora Naoko Okayama Yuichiro Yamada Yasuhiko Wada Shin Amemiya Shigetaka Sugihara Yuzo Nakao Yoshitomo Oka Yukio Tanizawa

BACKGROUND Wolfram syndrome (WFS) is a recessive neurologic and endocrinologic degenerative disorder, and is also known as DIDMOAD (Diabetes Insipidus, early-onset Diabetes Mellitus, progressive Optic Atrophy and Deafness) syndrome. Most affected individuals carry recessive mutations in the Wolfram syndrome 1 gene (WFS1). However, the phenotypic pleiomorphism, rarity and molecular complexity of...

ژورنال: :مجله دانشگاه علوم پزشکی مازندران 0
حمیدرضا ذاکری h.r zakeri فوق تخصص غدد، استادیار دانشگاه علوم پزشکی مازندران کیومرث نوروزپوردیلمی k nowroozpoor dailami

wolfram یا didmoad syndrome یک بیماری نادر ژنتیکی است که همراه با بیماری هایی نظیر دیابت، دیابت بیمزه، آتروفی عصب اپتیک و بعضی اختلالات نورولوژیک دیگر می باشد. بیمار حاضر، دختر 23 ساله ای است که با این تشخیص معرفی می گردد.

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