نتایج جستجو برای: diclofenac sodium
تعداد نتایج: 190906 فیلتر نتایج به سال:
The study was designed to examine the binding of diclofenac sodium with bovine serum albumin (BSA) at different temperatures (20 degrees, 30 degrees and 40 degrees C), pH (6.4, 7.4 and 8.4) and ionic strengths (micro = 0.1, 0.2 and 0.3) by means of equilibrium dialysis method. The concentration of diclofenac sodium was maintained at wider range from 15 to 900 micromole/l and BSA concentration w...
Aim: Ibuprofen400mg and Diclofenac Sodium 50mg marketed today inhibit Cox-1 and Cox-2 and have selectivity for Cox-1. Ibuprofen 400mg is an established analgesic in the management of acute dental pain. Diclofenac Sodium 50mg is also used in the management of acute pain, but there are very few studies comparing its analgesic efficacy with Ibuprofen. Materials and Method: A double blind randomize...
Background and Aims: Despite the significant improvement in dentistry, pain after endodontic therapy is still of concern for patients. Non-steroidal anti-inflammatory drugs are the most commonly prescribed oral analgesics used for dental pain relief after root canal treatment. The purpose of this study was to compare the effectiveness of Ibuprofen versus slow-released Diclofenac Sodium in contr...
Fifty male Sprague-Dawley rats were equally divided randomly into five groups to asses the protective and therapeutic effects of fucoidan against diclofenac sodium induced hepatonephrotoxicity. Elevated serum enzyme, increase expression of TLR4, massive hepatic necrosis, fibrosis, calcified mitochondria besides nephritis and coagulative necrosis of renal epithelium were noticed in rats intramus...
Introduction: Urinary calculi is the second common chronic renal disease. Todays, the extracorporeal shock wave lithotripsy (ESWL) is the most common method of treatment of kidney calculi, though this method was invented 30 years ago. This study was conducted to compare the effects of oral diclofenac sodium versus acetaminophen codein on pain during ESWL. Methods: After signing informed consen...
Background and Aim: Considering the increasing drug resistance to Aspergillus fumigatus, search for genes involved in its pathogenicity and identifying alternative antifungal drugs is of utmost importance. The aim of this study was to determine the effects of diclofenac sodium on the growth and sidB gene expression in Aspergillus fumigatus. Materials and Methods: In this study, Aspergillu...
Background: The aim of this study was to evaluate the analgesic effects of Alpha Pinene in writing and plantar pain tests in rats. Methods: This study was performed on male Wistar rats. Group 1: Normal saline was administered intraperitoneally (IP). Group 2: Diclofenac sodium at a dose of 5 mg/kg was administered (IP). Group 3: Alpha Pinene was administered (IP) at a dose of 0.1 mg/kg. Group ...
PURPOSE Gastrointestinal (GI) side effects of the nonsteroidal anti-inflammatory drug (NSAID) diclofenac may be reduced if it is administered as a complex with phospholipid. The upper and lower GI permeability induced by a diclofenac-dipalmitoyl phosphatidyl choline (DPPC) complex were compared with those of diclofenac acid and its sodium salt in rats. METHODS Pharmacokinetic studies were car...
Three simple, rapid, precise and accurate spectrophotometric methods have been developed for simultaneous analysis of Tolperisone Hydrochloride (TOL) and Diclofenac Sodium (DIC) in their combined dosage form. Method A, Simultaneous equation method (Vierodt’s method) applies measurement of absorptivities at two wavelengths, 261.00 nm (λmax of Tolperisone Hydrochloride) and 279.00 nm, (λmax of Di...
The objectives of present investigation were to achieve immediate release of paracetamol and tailored release of diclofenac sodium from bi-layer tablets. A 2(3) full factorial design was adopted using the amount of polyethylene glycol, microcrystalline cellulose and crospovidone as independent variables for fabricating paracetamol tablets. Diclofenac sodium tablets were prepared using hydroxypr...
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