Kaolin-SO3H nanoparticles were prepared via reaction of kaolin and chlorosulfonic acid and characterized by FT-IR, XRD, FESEM, TEM, XRF, EDS, BET and TGA. The activity of this green catalyst was probed by the synthesis of aryl diazonium salts as the starting reactant and then, their diazo coupling with  2-naphthol to form azo dyes in a solvent-free medium at room temperature...

Whereas previous studies have shown that opening of the mitochondrial ATP-sensitive K(+) (mitoK(ATP)) channel protects the adult heart against ischemia-reperfusion injury, it remains to be established whether this mechanism also operates in the developing heart. Isolated spontaneously beating hearts from 4-day-old chick embryos were subjected to 30 min of anoxia followed by 60 min of reoxygenat...

Haemoglobin interference in the determination of bilirubin was compared in 7 different methods using the Jendrassik-Grof procedure, the Jendrassik-Grof-Nosslin modification, and the more recent procedures using nitrophenyldiazonium, 2,5-dichlorophenyldiazonium, 2,4-dichloraniline, and a direct reading method. To a variable degree, haemoglobin decreased the apparent absorption of the reaction pr...

We report herein the asymmetric coupling of flow-generated unstabilized diazo compounds and propargylated amine derivatives, using a new pyridinebis(imidazoline) ligand, a copper catalyst and base. The reaction proceeds rapidly, generating chiral allenes in 10-20 minutes with high enantioselectivity (89-98 % de/ee), moderate yields and a wide functional group tolerance.

Sufficient coupling with any of five different diazo compounds eventually destroyed the reactivity of all the antisera here studied. The rates of inactivation varied considerably among the several antisera. By stopping the reaction at intervals, it was possible to prepare partially inactivated antibodies of peculiarly modified reactivity. Thus, the flocculating activity of diphtheria antitoxin ...

The coupling of aromatic diazo compounds with compounds containing a reactive methylene group to form 'mixed' azo compounds (tautomeric with hydrazones) was recognized as a general reaction following Meyer's (1877) synthesis of phenylazoacetoacetic ester from benzenediazohydroxide and ethyl acetoacetate. Japp & Klingemann (1888) found that when equimolar amounts of acetoacetic acid and benzened...

A method is described which provides for the direct asymmetric catalytic synthesis of trisubstituted aziridines from imines and diazo compounds. While unactivated imines were not reactive to α-diazo carbonyl compounds in which the diazo carbon was disubstituted, N-Boc imines react with both α-diazo esters and α-diazo-N-acyloxazolidinones to give trisubstituted aziridines with excellent diastere...