We report here on the coordination properties of a series lanthanide cations (Ln=La, Nd, Eu, Tb, Er) with tripodal homoditopic ligand L, which is bearing three diamido-dihydroxamate arms anchored tertiary amine. The complexes L lanthanides were studied in MeOH/H2O (80/20 by weight) solvent and marked size-discriminating effect depending intramolecular interactions was observed dinuclear edifice...

A series of 8 new complexes of titanium and zirconium with diamido ligands bearing an ethylene and propylene bridge between the two amido groups were synthesized and tested for ethylene polymerization. Titanium complexes bearing an ethylene bridge between the two amido groups showed higher activities than the derivatives with a propylene bridge. In the case of the zirconium complexes, the p...

The butyl urea of guanosine (UG) presents an ADDA hydrogen-bonding array that is complementary to the DAAD array of 2,7-diamido-1,8-naphthyridine (DAN). The stability of the DAN.UG complex was measured by fluorimetry using the fluorescence resonance energy transfer (FRET) from the naphthyridine ring to a coumarin 343 moiety linked covalently to the UG unit. The quadruply hydrogen-bonded complex...

The anionic diamido N-heterocyclic carbene 1 is used to prepare a series of linear as well trigonal, heteroleptic CuI complexes with small molecular ligands such pyridine derivatives or triphenylphosphine. A key role lies in the versatile precursor for these complexes, moisture- and air-stable 1D coordination polymer [1·Cu]n composed only NHC ligand CuI, that copper linearly coordinated by carb...

The facile coupling of azobenzene dyes to the quadruply hydrogen-bonding modules 2,7-diamido-1,8-naphthyridine (DAN) and 7-deazaguanine urea (DeUG) is described. The coupling of azobenzene dye 2 to mono-amido DAN units 4, 7, and 9 was effected by classic 4-(dimethylamino)pyridine (DMAP)-catalyzed peptide synthesis with N-(3-dimethylaminopropyl)-N'-ethyl carbodiimide hydrochloride (EDC) as activ...

A derivative of cyclophosphamide, 2,3-(TV, TV1-bis(2chloroethyl)diamido-l, 3, 2-oxazaphosphoridinoxyd (Iphosphamide), was less toxic in experimental systems than cyclophosphamide, while it had a broader antitumor spectrum. We studied this agent in a clinical trial of 37 patients with histologically proved, far-advanced malignant disease. The study was designed mainly to determine toxicity and d...