This review paper describes methods of protecting the peritoneal membrane in uremic patients chronically treated with peritoneal dialysis. Possible interventions involved in protection of the peritoneum aim at reducing peritoneal exposure to glucose, glucose degradation products and lactate; preventing or diminishing harmful effects of dialysis solutions; decreasing infection rate, especially p...

Substantial derangements of mesothelial biology are observed during experimental simulations of dialysis conditions, inferred from the content of human dialysis effluent and visualized by microscopy of human mesothelial biopsies. Can osmotically active solutions be made biocompatible with the osmoregulatory system of the mesothelium? Can the contributions of the mesothelium to host defenses aga...

..................................................................................................................... 10 Introduction ............................................................................................................... 12 Review of the literature .............................................................................................. 13 1. Principles of peritone...

An automated technic is described for the direct assessmentof l131-triiodothyronine binding by serum. The adsorbantsusedin the manual technics are replaced by dialysis. The radioactivity in the dialysate is measured in a continuous-flow scintillation system. Results obtained from 71 patients of varying thyroid status compare favorably with those of a standard manual I’31-triiodothyronine resin ...

In the present investigation the existence of "free" thyroxine in human serum was repeatedly verified by dialysis through cellophane, with paper chromatographic identification of thyroxine in the dialysate. Methods were developed for measurement of the minute amount of thyroxine present in the dialysate that was considered to represent the unbound or diffusible fraction of the hormone in serum....

Traditionally, peritoneal dialysis is performed using a volume of 2 l of fluid, containing glucose as an osmotic agent and lactate as a buffer. Currently, both the volume to be applied and the composition of the dialysis solution are subject to discussion. An interesting contribution with respect to the value of pHneutral dialysis solutions is reported in this issue of Nephrology Dialysis Trans...