introduction: good radiographs are required for endodontic therapy and because some patient’s are intolerant to intraoral films and/or sensors, this can cause complications in endodontic treatment. extraoral film placement can be used to obtain clinically diagnostic and working radiographs. materials and methods: the no. 2 receptor was placed against the model ’ s cheek and centered in the mola...

psychodynamic clinicians have long stressed the role of defense mechanisms in diagnosis and treatment of their patients. however, until recently the defense mechanisms were not the focus of extensive empirical research due to methodological limitations. the inclusion of defensive functioning scale (dfs) in dsm-iv has renewed the interest in psychodynamic approaches to clinical diagnosis, partic...

conclusions examining postural control as an endophenotype or early diagnostic marker of autism is a conceptual premise which should be considered in future investigations. at the end of the review, methodological recommendations on the assessment of postural control have also been provided. results individuals with asd have problems in maintaining postural control in infancy that well persists...

background: the initial step in the diagnostic investigation of male infertility has been traditionally based on the conventional seminal profile. however, there are significant limitations regarding its ability to determine the underlying mechanisms that cause the disorder. sperm dna fragmentation has emerged as a potential causative factor of reproductive failure and its assessment has been s...

BRAF inhibitors vemurafenib and dabrafenib achieved improved overall survival over chemotherapy and have been approved for the treatment of BRAF-mutated metastatic melanoma. More recently, the combination of BRAF inhibitor dabrafenib with MEK inhibitor trametinib has shown improved progression-free survival, compared to dabrafenib monotherapy, in a Phase II study and has received approval by th...

To counter the host RNA silencing defense mechanism, many plant viruses encode RNA silencing suppressor proteins. These groups of proteins share very low sequence and structural similarities among them, which consequently hamper their annotation using sequence similarity-based search methods. Alternatively the machine learning-based methods can become a suitable choice, but the optimal performa...