background: diabetes mellitus (dm) is a health concern which leads to complications such as retinopathy. pakistan has 6.9 million people living with dm and this toll will be doubled by 2025. objective: to determine serum il-6 and il-17 of type 2 diabetes mellitus (t2dm) patients with retinopathy. methods: in this cross-sectional casecontrol study, 212 subjects enrolled which were categorized in...

introduction: diabetes can affect organs including the oral mucosa. there is a disagreement about the prevalence of oral mucosal disease in diabetic patients. we therefore decided to investigate more about that. the aim of this study was to determine the prevalence of soft tissue pathologies by assessing burning mouth and xerostomia in diabetic patients on the basis of type of diabetes and cont...

angiotensin i-converting enzyme (ace) gene polymorphism; genotype dd or d allele may be involved with an increased susceptibility to type 2 diabetes and diabetic nephropathy (dn). we examined the frequency of ace gene polymorphism in 170 patients (85 type 2 diabetes with nephropathy and 85 without it) in tehran, iran. dna was extracted from the white blood cells and the i/d polymorphism of the ...

introduction: idiopathic pulmonary fibrosis (ipf) is a relentlessly progressive and usually fatal lung disease of unknown etiology for which no effective treatments currently exist. in the adults type i and ii pneumocytes, forms components of the alveolar epithelial cells. in this study, we investigated the effect of thalidomide on the alveolar epithelial cells (type i and ii pneumocytes) in th...

in an attempt to determine the clinical value of frnctosamine assay for monitoring type ii diabetic patients, correlation of frnctosamine with glycosylated hemoglobin was studied. 100 patients with type ii diabetes mcllitus were compared with 100 normal subjects. fasting blood glucose, glycosylated hemoglobin, albumin and frnctosamine were measured in alt subjects. in the diabetic patients, a s...

objective: the aim of the present study was to investigate the prevalence of hypertension and type ii diabetes in elderly iranianresidents of the kahrizak charity foundation(kcf). materials and methods: in this cross-sectional study, a total of two hundred sixty eight men and women ≥60 years were studied. the data were collected during annual health examination of the elderly residents in kcf. ...

background: diabetic nephropathy is considered to be the most common cause of end stage renal disease (esrd). proteinuria is declared as the most marked risk factor in progression towards esrd. the aim of this study was to evaluate the efficacy of pentoxifylline for reduction of proteinuria in type ii diabetic patients. methods: from may 2007 to june 2008, this randomized clinical trial study w...

Background: Angiotensin I converting enzyme (ACE) is a Zinc metalloproteinase, converts Ang-I to Ang- II, a pro-inflammatory agent which may contribute to pathophysiology of some diseases like type 2 diabetes. Objective: To investigate the relationship between ACE I/D polymorphism and type 2 diabetes in 261 Iranian casecontrol pairs. Methods: 170 patients (85 type 2 diabetics with nephropathy a...

background: visfatin is a new adipocytokine which is largely secreted by visceral adipose tissue and its effects in the development of diabetes and inflammatory reactions are similar to insulin. it acts synergistically with insulin in increasing glucose cellular uptake, stimulating glucose transfer to the muscle and adipose tissue, as well as in preventing hepatic glucose production. its insuli...