Lecithin and lecithin/cholesterol dispersions as well as lysolecithin micelles were used to provide basic information on the mechanism of the interaction of zwitterionic phospholipids with dextran sulfate. The addition of dextran sulfate to lecithin dispersions or lysolecithin micelles in the presence of Ca2+ produced insoluble complexes. At each Ca2+ concentration, the amount of insoluble comp...

The interaction between dextran sulfate and low-density lipoproteins of the Sr 0-10 class in phosphate buffer of pH 7.4 and ionic strength 0.1 was studied by means of analytical ultracentrifugation. The sedimentation pattern of the dextran sulfate-lipoprotein mixture at high dextran sulfate/lipoprotein weight ratios showed a boundary indicative of a soluble complex with a high sedimentation rat...

Several well-known anticoagulants are in use for blood sample tubes, each having some special application, but there is little doubt that the naturally occurring anticoagulant, heparin, would find wider application were it not so difficult to prepare and consequently expensive. Chemically prepared sulphuric esters of polysaccharides are known to have anticoagulant action. One of these, dextran ...

Ophthalmological Society of the United Kingdom.Annual congress will be held on April 26-28, 1956, at the Royal Society of Medicine, London. The main subject for discussion will be "The Early Diagnosis of Glaucoma." Members wishing to contribute should notify the hon. congress secretary at 45, Lincoln's Inn Fields, London, W.C.2, not later than November 30. The annual dinner will be on April 26,...

In this study, dextran-encrusted magnetic nanoclusters (DMNCs) were synthesized using a one-pot solution phase method for detection of atherosclerosis by magnetic resonance imaging. Pyrenyl dextran was used as a surfactant because of its electron-stabilizing effect and its amphiphilic nature, rendering the DMNCs stable and water-dispersible. The DMNCs were 65.6±4.3 nm, had a narrow size distrib...

A total arrest of cell membrane movement occurred after incubation for 2 h of cultured fibroblasts with the polycation DEAE-dextran. The immobilized cells resumed normal membrane undulations after exposure for 5 min to the polyanion dextran-sulphate. The influence of DEAE-dextran on the electrophoretic mobility, which was seen after 10 min of incubation was also erased by a subsequent incubatio...

In the work the thermal behaviour of the magnetic nanoparticles modi ed with polysaccharide dextran of di erent weight ratios to the magnetite Fe3O4 was investigated using thermoanalytical methods di erential scanning calorimetry and thermogravimetric analysis. The adsorption of dextran on the magnetic nanoparticles was con rmed and the in uence of the dextran amount in the modi ed magnetic uid...

The interactions of dextran sulfate with high density lipoproteins (HDL) and with low density lipoproteins (LDL) were studied to differentiate their mechanisms and to provide some information of the charge characteristics of these lipoproteins. The insoluble complex formation with high density lipoprotein 3 (HDL3) progressively increased with increases of the Ca2+ concentration; complete conver...

Synthesized thiolate boronic acid was found to complex with both a polysaccharide (dextran) and a monosaccharide (glucose) with similar affinities but displayed more affinity with dextran than with glucose when capped as a ligand on silver nanoparticle. Coupling on multiple sites of dextran, the silver particles were aggregated. The aggregated particles displayed a decrease of absorbance at 397...