Previous research has identified the nominal group as the most distinctive feature of the research article title. In contrast, the findings reported in this paper suggest Theme/Rheme is the dominant structure in title text. Theme/Rheme structures order and tie nominal groups in titles. When a title starts with a methodological term the first position nominal group acts as a theme marker. Thus, ...

Mathematical methods provide useful framework for the analysis and design of complex systems. In newer contexts such as biology, however, there is a need to both adapt existing methods as well as to develop new ones. Using a combination of analytical and computational approaches, we adapt and develop the method of describing functions to represent the input-output responses of biomolecular sign...

Describing function is an equivalent gain of nonlinear element, defined by the harmonic linearization method of nonlinear static characteristic (Novogranov, 1986, Slotine and Li, 1991, Schwarz and Gran, 2001, Vukic et al. 2003 and many others). It is a known method of analysis and synthesis when nonlinear system can be decoupled into linear and nonlinear parts (Fig. 1). If the linear part of th...