In the present chapter we discuss methodologies for the modelling, calibration and validation of cellular signalling pathway dynamics. The discussion begins with the typical range of techniques for modelling that might be employed to go from the chemical kinetics to a mathematical model of biochemical pathways. In particular, we consider the decision making processes involved in selecting the r...

In the present chapter we discuss methodologies for the modelling, calibration and validation of cellular signalling pathway dynamics. The discussion begins with the typical range of techniques for modelling that might be employed to go from the chemical kinetics to a mathematical model of biochemical pathways. In particular, we consider the decision-making processes involved in selecting the r...

Signalling in multicellular organisms is mediated by complex networks that integrate extracellular and intracellular signals to generate appropriate responses regulating cell proliferation, differentiation and survival. Downstream of many cytokine and growth hormone receptors, receptor-associated JAKs ( Janus kinases) activate transcription factors of the STAT (signal transducer and activator o...

soil compaction reduces growth of secondary roots, soil aeration and water and mineral uptake by plant, and decreases chlorophyll content as well as root yield and sugar content. hence, the effect of soil compaction on sugar beet yield and sugar content farms determined by penetrometer using 40 plots of 100 m2 in 40 sugar beet field of hamedan, asadabad, malayer and bahar at the depth of 0-80 c...

Populations of culturable microbes and activeties of dehydrogenase & β-D glucosidase were found maximum in surface soil and decreased with increase in depth in Sundarban mangrove environment. The maximum (13.529 × 10 C.F.U g dry weight of soil) and minimum (11.547 × 10 C.F.U g dry weight of soil) total microbial populations in surface soil were recorded during post-monsoon and monsoon respectiv...

1991). These properties include soil bulk density and chemical properties. This study investigated the relationships between corn (Zea mays An objective of site specific management is to apply L.) grain yield and weather over a range of soil rooting depths with appropriate levels of agricultural inputs to localized areas. and without irrigation. The purpose was to test if variability of corn Si...

A GIS method for modeling landscapes to predict total soil depth and the depth of different soil layers is presented. The method is based on terrain analysis using a DEM and the combined use of the Topographic Wetness Index (TWI) also known as the Compound Topographic Index (CTI) and the Multi-resolution Valley Bottom Flatness index (MrVBF). Examples of the output for several catchments show th...

This paper employs one-dimensional numerical ground response analysis models to investigate seismic response of shallow cohesive and non-cohesive soil deposits on vertical propagation of horizontal shear waves. Soil response is modelled by traditional equivalent-linear (EL) frequency-domain analysis using DEEPSOIL software and nonlinear (NL) time-domain analysis using OPENSEES software. The ana...

abstract information on spatial and temporal variations of soil hydraulic conductivity (k) is essential to improve soil and water management. however several techniques have been proposed for measuring of soil hydraulic conductivity above water surface table, but reliability and easy use of these methods in various conditions were always concern for engineers. the purposes of this study are mea...

A series of field experiments was conducted at BARI central farm to observe the changes in soil densities, moisture retentive properties, and crop productivity as influenced by different tillage depths and cropping patterns. The tillage depth showed significant effect on wheat yield. Grain yield of wheat significantly increased from 2.86 t/ha (minimum tillage depth) to 5.33 t/ha (tillage depth ...