Vitiligo is one of the most common pigmentary skin disorders; it is characterized by circumscribed depigmented macules due to the destruction of melanocytes. Although the etiology of vitiligo has not been fully elucidated, multiple factors including autoimmune and oxidative stress have been implicated in the pathogenesis of vitiligo. In contrast, dermal melanocytosis is histologically character...

Background: Cutaneous findings in the setting of HIV infection encompass a broad spectrum of diseases. Only few cases of vitiligo or alopecia areata have been described in HIV/AIDS patients and it remains unclear whether there is a causal relationship between HIV/AIDS and these two conditions. Observations: Our patient initially presented with diffuse generalized pruritic hypoand depigmented ma...

ABSTRACT Vitiligo is a dermatological disease affecting both animals and humans. It characterized by depigmented macules of varying shape size, originated from melanocyte destruction. Even though there are some theories tackling causation, etiopathology not yet certain. Moreover, lesion areas can either increase or diminish over time, therefore, available treatment alternatives tend to prove in...

Vitiligo is an usual acquired pigmentary disorder of the skin characterized by well-circumscribed depigmented macules and patches. Though association between vitiligo thyroid disorders has been suggested, only a few studies from India overseas have paid attention to describe abnormalities, particularly in children. Hence, this study was taken up for evaluating disease childhood compared control...

Background: Vitiligo is an autoimmune pigment disease, and marked by well-defined depigmented patches or macules attributable to the loss of functioning melanocytes in epidermis hair infundibulum. Objective: To test serum levels Vitamin D contrast effects controls vitligo patients.Methods: It a case-control study conducted hospital setting that involves 100 patients out which 50 cases controls....

Depigmented haloes sometimes appear around melanocytic tumors or non-melanocytic tumors, but coexistence of warts and depigmented haloes is extremely rare. We report here an unusual case of warts accompanied by depigmented haloes and subsequently-triggered generalized vitiligo. A 55-year-old Japanese man presented with a 3-year history of brown nodules on the back, upper eyelid and dorsum of th...

A 50 year old male presented with progressive difficulty in swallowing both liquid and solid food with no history of Raynaud's phenomenon. A general examination revealed skin changes in the form of thickening, hyperpigmentation and tightening of skin of fingers, hand, forearm and legs. The patient had painless skin induration over the legs, forearm and hand. Salt and pepper pigmentation was see...

BACKGROUND Immunogenicity studies are based on accurate preclinical and clinical assessment of pharmaceutical products. The immunogenicity of modified allergen vaccines has not been fully elucidated, and the mechanisms involved are not well understood. Animal and human models have recently shown that depigmented allergoids induce specific immunoglobulin (Ig) G against individual allergens, thus...

In the examination of leprosy patients my attention has been arrested by a peculiar affection of the follicular structure of the skin that, so far as known to me, has not been described heretofore. In K lingmiiller's exhaustive review of leprosy (4), which comprises the world's literature up to 1930, there are no indications that this condition has been recorded. Among the reports on leprosy th...