Critically ill patients often suffer from disturbance of sleep-wake cycle and consequently delirium development, in intensive care units (ICU). In this study, we aimed to evaluate the effect of exogenous melatonin on delirium development and its related adverse sequelae in the subgroup of medical and surgical ICU patients. We performed a double-blind placebo-controlled randomized pilot study i...

Delirium is a syndrome consisting of cloudiness of consciousness,attention deficit,and cognitive impairment,with quick onset,but varring paths in its progression .delirium is more common after major surgeries in the elderly and hospitalized patients,resuting in high morbidity and mortality rates.the incidence rate that has been reported  in previous studies varies from 1-3% in cataract surgery ...

1. Explain theories of the pathogenesis of delirium. 2. Assess patient risk factors for delirium. 3. Analyze patient drug regimens to determine the likelihood that delirium or delirium-like symptoms are drug related. 4. Adjust a patient’s drugs to prevent delirium. 5. Prepare a patient care plan that includes patient-specific pharmacologic and nonpharmacologic methods to prevent delirium. 6. Co...

BACKGROUND Delirium is an acute change in cognition and concentration that complicates the postoperative course. Patients who suffer delirium after surgery have an increased risk of persistent cognitive impairment, functional decline, and death. Postoperative delirium is also associated with an increased length of hospital stay and higher costs. With the goal of preventing delirium in postopera...

The aim of the study was to determine duration of delirium in patients with acute stroke according to sex, age, type and localization of lesion. We assessed delirium prospectively in a sample of 233 consecutive patients with an acute (< or =4 days) stroke using the Delirium Rating Scale (DRS-R-98) and Diagnostic and Statistical Manual of Mental Disorders (DSM IV). The average duration of deliri...

BACKGROUND Delirium phenomenology is understudied. AIMS To investigate the relationship between cognitive and non-cognitive delirium symptoms and test the primacy of inattention in delirium. METHOD People with delirium (n=100) were assessed using the Delirium Rating Scale-Revised-98 (DRS-R98) and Cognitive Test for Delirium (CTD). RESULTS Sleep-wake cycle abnormalities and inattention wer...

normal 0 false false false en-us x-none ar-sa background: coronary artery bypass graft is one of common cardiac surgeries which unfortunately accompany with some adverse events such as delirium. proinflammatory processes play an important role in pathogenesis of post-operative delirium. therefore, the effect of dexamethasone (dex) on post-operative delirium after cardiac surgery was evaluated. ...

BACKGROUND Between 10 % to 48 % of patients develop delirium in acute phase of stroke. Delirium determinants and its association with other neuropsychiatric disturbances in stroke are poorly understood. The wildly accepted predictive model of post-stroke delirium is still lacking. METHODS/DESIGN This is a prospective, observational, single-center study in patients with acute phase of stroke. ...

BACKGROUND Delirium is a prevalent problem in long-term care (LTC) facilities where advanced age and cognitive impairment represent two important risk factors for this condition. Delirium is associated with numerous negative outcomes including increased morbidity and mortality. Despite its clinical importance, delirium often goes unrecognized by nurses. Although rates of nurse-detected delirium...