purpose: to report complications involving the posterior segment after laser assisted in situ keratomileusis (lasik) in 5 myopic patients ranging in age from 26 to 38 years. patients and findings: case one developed bilateral cilioretinal artery obstruction in association with ischemic optic neuropathy. case two presented with nonsimultaneous bilateral delayed-onset optic neuropathy. in case th...

Dear Editor, We previously reported a case of delayed autonomic neuropathy in a patient with diethylene glycol (DEG) poisoning, and would like to emphasize two characteristic complications, sensorimotor neuropathy and renal failure, occurring in the same case, because of their severity and possible reversibility. Although once recovered from acute symptoms by day 3, the patient suffered from lo...

TO THE EDITOR: I read with great interest the paper entitled “Gastroesophageal reflux disease in type II diabetes mellitus with or without peripheral neuropathy” by Lee et al, which was published in July 2011 issue of Journal of Neurogastroenterology and Motility. The authors investigated gastroesophageal reflux disease (GERD) among patients with type II diabetes mellitus, and showed interestin...

Muslin-induced optic neuropathy is a rarely reported but important cause of delayed visual loss after repair of intracranial aneurysms. Most of the previously reported cases were published before the introduction of MR imaging. We describe the clinical features and MR appearance of two cases of delayed visual loss due to "muslinoma," and compare them with the 21 cases reported in the literature.

Neuropathy target esterase (NTE) is inhibited by several organophosphorus (OP) pesticides, chemical warfare agents, lubricants, and plasticizers, leading to OP-induced delayed neuropathy in people (>30,000 cases of human paralysis) and hens (the best animal model for this demyelinating disease). The active site region of NTE as a recombinant protein preferentially hydrolyzes lysolecithin, sugge...

Case A 72-year-old man presented to our hospital after ingesting insecticide containing approximately 2 mL/kg diethylene glycol, which exceeded the lethal dose of 1 mL/kg. The patient recovered from critical symptoms on acute phase until day 3, but received artificial ventilation for muscle weakness secondary to sensorimotor neuropathy on days 11-54. Outcome Even after marked improvement from...

Cobalamin neuropathy was produced in Cape fruit bats (Rousettus aegyptiacus) by a cobalamin-free diet combined with intermittent exposure to nitrous oxide, which inactivates cobalamin. Cobalamin-deficient bats had low hepatic methylmalonyl-CoA mutase holoenzyme activity, with elevated plasma and urinary methylmalonic acid levels. No significant changes could be demonstrated in the concentration...

as a result of higher distributed consanguinity in the mediterranean region and the middle east, autosomal-recessive forms of charcot-marie-tooth (arcmt) are more common in these areas. cmt disease caused by mutations in the ganglioside-induced differentiation-associated protein 1 (gdap1) gene is a severe autosomal recessive neuropathy resulting in either demyelinating cmt4a neuropathy or axona...