The human body loses several billions of cells daily. When cells die in vivo, the corpse of each dead cell is immediately cleared. Specifically, dead cells are efficiently recognized and cleared by multiple types of neighboring phagocytes. Early research on cell death focused more on molecular mechanisms of cell death regulation while the cellular corpses were merely considered cellular debris....

Electrochemical impedance spectroscopy (EIS) is a suitable and powerful diagnostic testing method for fuel cells (FCs) since it is non-destructive and provides useful information about FC performance and its components. In this study, for the first time, a 500W cascade type 4 cells stack with integrated humidifier, water separator and internal manifolds was designed, fabricated and tested. The ...

Forty-four female students with a tendency for constipation (mean age, 20.2±3.3 y) were asked to consume 30 g test pickles daily for 2 wk and were divided into 3 groups: viable-cell intake subjects (n=14, 3.0×10⁵ colony-forming units of viable LAB (lactic acid bacteria) cells per sample), dead-cells intake subjects (n=15, viable cells were heat sterilized), and placebo-intake subjects (n=15, LA...

INTRODUCTION Many antitumor therapies induce apoptotic cell death in order to cause tumor regression. Paradoxically, apoptotic cells are also known to promote wound healing, cell proliferation, and tumor cell repopulation in multicellular organisms. We aimed to characterize the nature of the regenerative signals concentrated in the micromilieu of dead and dying cells. METHODS Cultures of viab...

CONGESTIVE HEART FAILURE represents the end stage of various cardiac disease etiologies, including hypertension, myocardial infarction/ischemia from atherosclerosis, viral myocarditis, valvular insufficiency, or mutations in genes encoding sarcomeric proteins (1, 10, 11). These events trigger neurohumoral and cellular signaling cascades, ultimately resulting in myocardial adaptation, typically ...

Membrane-damaged cells caused by either mechanical trauma or through normal biological processes can produce artifacts in immunophenotyping analysis by flow cytometry. Dead cells can nonspecifically bind monoclonal antibody conjugates, potentially leading to erroneous conclusions, particularly when cell frequencies are low. To date, DNA intercalating dyes (Ethidium monoazaide (EMA), Propidium I...

This article illuminates the transmedia storytelling techniques in The Walking Dead comic book and video game. Telltale Games’ The Walking Dead localizes itself within the comic book world of The Walking Dead by acting as a transmedia storytelling device and using intertextuality comics to assist game players with meaning-making. By participating in the game, Telltale rewards players with addit...

Despite significant advances in our understanding or renal tubular cell function, the in vivo handling of E. coli by renal tubules has not been previously investigated. The present studies were, therefore, designed to study this aspect of nephron function. Live and dead E. coli and vehicle alone were microinjected into the proximal tubular lumen of a single nephron of rats, and the microinjecte...

The Dead Sea is one of the saltiest bodies of water in the world. Observational evidence has been obtained of unexpected short-term water heating in the 2-m uppermost layer of this hypersaline lake, following a sharp drop in solar radiation under weak winds. This was carried out using Dead Sea buoy measurements. Passing frontal cloudiness mixed 30 with significant dust pollution over the Judean...