It is well established that gonadotropin-releasing hormone receptors (GnRH-R) are expressed in different types of cancers, including castration-resistant prostate cancer (CRPC) and mediate the antiproliferative effect of GnRH analogs. Thus, these compounds are employed as targeting moieties to selectively deliver chemotherapeutic agents to cancer cells. GnRH-III, the decapeptide isolated from t...

1 Formal Logic with Conceptual Graphs 3 Frithjof Dau 1.

In this study, polybrominated diphenyl ethers (PBDEs), hexabromocyclododecanes (HBCDs) and polychlorinated biphenyls (PCBs) were determined in human scalp hair from Vietnam. Levels of PBDEs and HBCDs were significantly higher in hair of e-waste recycling workers in Bui Dau (e-waste recycling site), an e-waste recycling site than those in general residents in Bui Dau, Dong Mai (lead battery recy...

Fourier transform of gated radionuclide ventriculograms (RNV) permits the quantitative evaluation of regional wall motion abnormalities (RWMA) regarding both regional magnitude (amplitude display) and regional time sequence of contraction (phase display). In this study, an attempt was made to further specify coronary artery disease (CAD) and non-CAD RWMA detected on consecutive exercise RNV in ...

Calmodulin inhibitors enhance cytotoxic effects of doxorubicin (DOX) in DOX-resistant (P388/DOX) P388 mouse leukemia cells by increasing cellular accumulation and retention of drug. In P388/DOX cells treated for 3 hr, cytotoxic effects (based on colony formation in soft agar) of daunorubicin (DAU) in the presence of trifluoperazine (TFP) were DAU concentration-de pendent and enhanced 2to 100-fo...

Daunomycin and other structurally related anthracyclines can cause myelosuppression and cardiomyopathy. We explored the possible mechanism(s) by which daunomycin (DAU) interacts with target sites in neoplastic hemopoietic cells and heart tissue. We observed that | 'lli(. i|l) VI interacts selectively with mitochondria! hemoproteins isolated from K-562 cells and rat and bovine heart and forms re...

Pendapatan Asli Daerah (PAD) dan Dana Alokasi Umum (DAU) ialah dana daerah untuk menganggarkan Belanja Modal (BM) dalam menyediakan fasilitas layanan masyarakat agar menciptakan Pertumbuhan Ekonomi inklusif (PE), sehingga kesejahteraan dapat terpenuhi. Tujuan penelitian ini menguji hipotesis pengaruh PAD DAU terhadap BM, BM memediasi PE, PE masyarakat, kemungkinan Flypaper Effect pada BM. Popul...

The aim of this research is to demonstrate how the Yogyakarta Special Region's DAU, DAK, and PAD will affect economic growth from 2013 2020. quantitative technique study employed a multiple linear regression analysis ascertain association between variables in Region Yogyakarta. population was City/Regency years results show that DAU negatively Yogyakarta's Between 2020, economy grew favorably a...

BACKGROUND Among birch pollen allergic patients up to 70% develop allergic reactions to Bet v 1-homologue food allergens such as Api g 1 (celery) or Dau c 1 (carrot), termed as birch pollen-related food allergy. In most cases, specific immunotherapy with birch pollen extracts does not reduce allergic symptoms to the homologue food allergens. We therefore genetically engineered a multi-allergen ...