OBJECTIVE To assess the effectiveness, drug survival and safety of tocilizumab compared with TNF-α inhibitors in clinical practice. METHODS Patients in the Cohort of Arthritis Biologic Users at Kameda Institute (CABUKI) registry who were on biologics during July 2003 to October 2010 were included. Remission rates at 6 months, Kaplan-Meier drug survival estimates and serious adverse event (SAE...

BACKGROUND Rheumatoid arthritis (RA) is a common autoimmune disease that is associated with progressive disability, systemic complications, and early death. The present study was aimed to investigate the level of immunoglobulin G (IgG) and IgA isotypes and anti-cyclic citrullinated peptide (CCP) antibody and to assess their association with disease severity based on disease activity score (DAS-...

Treating rheumatoid arthritis (RA) to target is advocated using disease activity measures. The impact of RA on the general health status of affected patients in Jordan is not well described. This study reported the severity of RA in Jordan and its association with consequent disabilities and comorbidities. A cross-sectional, observational study was conducted at King Abdullah University Hospital...

AIM To detect level of serum vitamin D in patients of Rheumatoid arthritis (RA) and to establish relationship between serum vitamin D level and disease activity in RA. METHOD Eighty patients of RA fulfilling 1987 revised criteria of the American College of Rheumatology (ACR) of RA classification and eighty healthy controls were included in the study. 25 (OH) vitamin D levels were measured. Di...

Objectives. To evaluate the impact of clinical response on work stoppage or work absence among employed people with early RA. Methods. First-year data from the combination of MTX and etanercept trial was used. The analyses were restricted to the 205 patients working full or part time at baseline who answered questions on whether they stopped working or missed days from work in one or more of th...

OBJECTIVES To evaluate the impact of clinical response on work stoppage or work absence among employed people with early RA. METHODS First-year data from the combination of MTX and etanercept trial was used. The analyses were restricted to the 205 patients working full or part time at baseline who answered questions on whether they stopped working or missed days from work in one or more of th...

Finger millet landraces viz., TZA-01 and TZM-01 were grown in glasshouses under two moisture regimes (fully irrigated and after drought) to investigate the effects of environmental stress on the growth, SPAD measurement, radiation use efficiency and yield of finger millet (Eleucine coracana). The drought treatment was imposed at 28 DAS beyond which no irrigation was applied to the droughted tre...

Von der Informationstechnologie (IT) wird auch bei Non-Profit-Organisationen (NPOs) zunehmend verlangt, dass diese flexibel, direkt und messbar zum geschäftlichen Erfolg beiträgt. Entsprechend wichtiger wird für eine NPO im Rahmen der IT Governance (ITG) die strategische Ausrichtung der IT. Val-IT bietet hierzu Leitlinien, Prozesse und unterstützende Praktiken für das Top Management. Eine Auswa...