Viral retinitis associated with herpesvirus is one of the most severe forms uveitis and a potentially sight-threatening ophthalmologic disease. The prognosis poor rapid aggressive management necessary to improve visual sometimes vital these patients. treatments used are not without side effects, while many differential diagnoses exist, such as toxoplasmic retinochoroiditis, syphilitic retinitis...

AIDS-related human cytomegalovirus (HCMV) retinitis remains the leading cause of blindness among untreated HIV/AIDS patients worldwide. Understanding the pathogenesis of this disease is essential for developing new, safe, and effective treatments for its prevention or management, yet much remains unknown about the virologic and immunologic mechanisms contributing to its pathology. To study such...

Purpose : To discuss the definition and to determine the most logical intervention in treating patients with clinically foscamet resistant cytomgalovirus retinitis. Patients : Two patients with foscarnet clinically resistant cytomegalovims retinitis were followed in our department since june 1994. In these 2 patients, foscarnet was the first antiviral drug theraw civen for the treamxnt of cvtom...

Purpose : To discuss the definition and to determine the most logical intervention in treating patients with clinically foscamet resistant cytomgalovirus retinitis. Patients : Two patients with foscarnet clinically resistant cytomegalovims retinitis were followed in our department since june 1994. In these 2 patients, foscarnet was the first antiviral drug theraw civen for the treamxnt of cvtom...

Six patients (11 eyes) with virologically confirmed cytomegalovirus (CMV) retinitis involving the posterior pole of the eye were treated with a new drug, ganciclovir. Treatment with intravenous ganciclovir consistently halted progression of retinitis and produced improvement in measures of visual function. However, within three weeks after cessation of therapy renewed CMV activity and worsening...

The eyes of an AIDS patient with cytomegalovirus (CMV) retinitis and pneumonitis who died while receiving maintenance therapy with the antiviral agent 9-[2-hydroxy-1-(hydroxymethyl) ethoxymethyl] guanine (Ganciclovir) were obtained for pathological examination. While under treatment the patient had significant improvement but not complete regression of retinitis. Electron microscopic and immuno...