ObjectiveTo test the hypothesis that telomere shortening and/or loss are risk factors for infertility.DesignRetrospective analysis of status in patients with infertility using conventional cytogenetic data collected prospectively.SettingAcademic centers.Patient(s)Cytogenetic slides cultured peripheral lymphocytes from 50 undergoing fertility treatment and 150 healthy donors, including 100 donor...

BACKGROUND Cytogenetic studies of malignant peripheral nerve sheath tumours (MPNSTs) and malignant triton tumours (MTTs) are rare. AIMS To undertake cytogenetic analysis of these tumours. METHODS Conventional cytogenetic analysis of 21 MPNSTs and MTTs from 17 patients (nine with peripheral neurofibromatosis (NF1)) was carried out using standard culture and harvesting procedures. For a more ...

Background Cytogenetic study of reproductive wastage is an important aspect in determining the genetic background of early embryogenesis. Approximately 15 to 20% of all pregnancies in humans are terminated as recurrent spontaneous abortions (RSAs). The aim of this study was to detect chromosome abnormalities in couples with RSAs and to compare our results with those reported previously. Materia...

background: chromosome abnormality (ca) including sex chromosomes abnormality (scas) is one of the most important causes of disordered sexual development and infertility. scas formed by numerical or structural alteration in x and y chromosomes, are the most frequently ca encountered at both prenatal diagnosis and at birth. objective: this study describes cytogenetic findings of cases suspected ...

background: acute lymphoblastic leukemia (all) is the sixth most common malignancy in iran. cytogenetic analysis of leukemic blasts plays an important role in classification and prognosis in all patients. the purpose of this study was to define the frequency of chromosomal abnormalities of all patients in adults and children in fars province, iran. methods: in this cross-sectional study, we eva...