Introduction: Recent research has reported the cytotoxic potential of hydrazones against various strains cancer cells. Aim: To evaluate anticancer activity in vitro and pharmacokinetic profile six synthesized hydrazonic compounds, identified as vanillin 1-phthalazinylhydrazone (VAN-1); 2,4-dinitrophenylhydrazone (VAN-2); phenylhydrazone cinnamaldehyde (CIN-1); isonicotinoyl hydrazone (CIN-2); 1...

Two membrane electrochemical reactors (MER) were designed and applied to HLADH-catalysed reduction of cyclohexanone to cyclohexanol. The regeneration of the cofactor NADH was ensured electrochemically, using either methyl viologen or a rhodium complex as electrochemical mediator. A semi-permeable membrane (dialysis or ultra-filtration) was integrated in the filter-press electrochemical reactor ...

The synthesis of 2,6-bis(hydroxy(phenyl)methyl)cyclohexanone 1 is described. The molecular structure of the title compound 1 was confirmed by NMR, FT-IR, MS, CHN microanalysis, and X-ray crystallography. The molecular structure was also investigated by a set of computational studies and found to be in good agreement with the experimental data obtained from the various spectrophotometric techniq...

Although considerable attention has been given to the identification of keto acids produced during the fermentation of glucose by Escherichia coli, relatively little information has been obtained on the production of aldehydes and ketones. During an investigation of the keto acids produced during glucose fermentation by E. coli 82/r and P6 (D. W. Thayer and J. E. Ogg, Bacteriol. Proc., p. 96, 1...

We describe efforts to understand the structure and reactivity of lithiated cyclohexanone N-cyclohexylimine. The lithioimine affords complex solvent-dependent distributions of monomers, dimers, and trimers in a number of ethereal solvents. Careful selection of solvent provides exclusively monosolvated dimers. Rate studies on the C-alkylations reveal chronic mixtures of monomer- and dimer-based ...

The current approach involves the kinetic investigation of Thiobenzamide (TB) and cyclohexanone thiosemicarbazone (CTSC) in solution with 3-chloroacetylacetone(3-CAA). study revealed a second-order rate constant respect to both reactants, thioamide an α-halo carbonyl compound. energy activation (Ea) was found be Ea 48.8176 kJ/mol/K for thiobenzamide 33.08692157 Cyclohexanone thiosemicarbazone. ...