N-alkyl azetidines bearing a chiral substituent at the nitrogen atom, and variable C-3 as prochiral centre, react readily with cyanogen bromide even low temperatures to produce corresponding 3-bromo-N-cyanamides diastereoisomeric mixtures via ring opening. This reaction was found be diastereoselective (up 80:20 dr). In one case, major diastereomer could isolated by recrystallization, configurat...

The cyanamides NCNR2 (R2 = Me2, Ph2, C5H10) react with ZnX2 (X = Cl, Br, I) in a 2 : 1 molar ratio at RT, giving a family of zinc(ii) complexes [ZnX2(NCNR2)2] (R2 = Me2, X = Cl , X = Br , X = I ; R2 = C5H10, X = Cl , X = Br ; X = I ; R2 = Ph2, X = Cl , X = Br , X = I ; 75-92% yields). Complexes and undergo ligand redistribution in wet CH2Cl2 solutions giving the [Zn(NCNPh2)4(H2O)2][Zn2(μ-X)2X4]...

The alkaline-earth metal cyanamides MgCN* SrCN* and BaCN 2 were prepared by the reaction of melamine with the metal nitrides (M&N2, Sr-jN, Ba 3 N 2 ) at temperatures between 740 e C and 850 °C. MgCN 2 was structurally characterized by X-ray analysis using powder methods (R3m, Ζ 3 , a=327.34(1) pm, c-1412.82(5) pm). The crystal structures of S r C N 2 and BaCN 2 were determined from X-ray single...

A fast and convenient synthesis of aryl amidines starting from carboxylic acids and cyanamides is reported. The reaction was achieved by palladium(II)-catalysis in a one-step microwave protocol using [Pd(O2 CCF3 )2 ], 6-methyl-2,2'-bipyridyl and trifluoroacetic acid (TFA) in N-methylpyrrolidinone (NMP), providing the corresponding aryl amidines in moderate to excellent yields. The protocol is v...

A one-pot, tandem process has been developed for the synthesis of a library of tetrazoles from aryl isothiocyanates. Condensation of aryl isothiocyanates with ammonia, and aryl amines (R-NH(2)) provided mono, 1,3-disubstituted symmetrical and unsymmetrical thioureas, which on desulfurization with molecular iodine (I(2)) led to formation of the corresponding heterocumulene (cyanamides or carbodi...