نتایج جستجو برای: cuzn superoxide dismutase

تعداد نتایج: 34128  

Journal: :Stroke 2000
K Sampei A S Mandir Y Asano P C Wong R J Traystman V L Dawson T M Dawson P D Hurn

BACKGROUND AND PURPOSE Both NO and superoxide cytotoxicity are important in experimental stroke; however, it is unclear whether these molecules act within parallel pathological pathways or as coreagents in a common reaction. We examined these alternatives by comparing outcomes after middle cerebral artery occlusion in male and female neuronal NO synthase (nNOS)-deficient (nNOS-/-) or human CuZn...

Journal: :Cancer research 1990
G J Hauser J K McIntosh W D Travis S A Rosenberg

The role of oxygen free radicals in the toxicity and antitumor effect of tumor necrosis factor was investigated in vivo. Treatment of non-tumor-bearing mice and mice bearing methylcholanthrene-induced sarcomas with bovine CuZn superoxide dismutase or recombinant human CuZn superoxide dismutase afforded significant protection to these mice from a subsequent challenge with recombinant human tumor...

Journal: :Journal of experimental botany 2006
Marja Hakala Susanne Rantamäki Eeva-Maija Puputti Taina Tyystjärvi Esa Tyystjärvi

Evidence has recently been presented that photoinhibition of photosystem II (PSII) is triggered by absorption of light by the oxygen-evolving manganese cluster. To get insight into the effects of light on enzymes containing manganese or other transition metal cofactors, the photosensitivities of Mn catalase, Mn superoxide dismutase, the haem (Fe)-containing bovine liver catalase, and CuZn super...

Journal: :Atherosclerosis 2000
P Strålin S L Marklund

Oxygen free radicals as well as immunological reactions have been suggested to play important roles in atherogenesis and other pathological processes of the blood vessel wall. We have previously shown that the vascular wall contains exceptionally large amounts of extracellular superoxide dismutase (EC-SOD) and that the enzyme is produced and secreted to the extracellular space by the smooth mus...

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