Granulomatous slack skin syndrome is a rare variant of mycosis fugoides characterized by the development of pendulous skin folds in the intertriginous regions. It has an indolent but progressive course and is usually refractory to treatment. Extra-cutaneous involvement is rare. We report a unique case of slack skin syndrome coexisting with a progressive granulomatous lung disease.

IMPORTANCE Hermansky-Pudlak syndrome (HPS) is a rare genodermatosis characterized by oculocutaneous albinism, platelet dysfunction, and in some patients, pulmonary fibrosis and granulomatous colitis. The granulomatous inflammation in the bowel of patients with HPS can be indistinguishable clinically and histologically from that of Crohn disease (CD); however, mucocutaneous granulomatous lesions...

BACKGROUND Granulomatous dermatoses are common skin pathology, often need histopathological confirmation for diagnosis. Histologically six sub-types of granulomas found in granulomatous skin diseases- tuberculoid, sarcoidal, necrobiotic, suppurative, foreign body & histoid type. The aims of the present study were clinico-pathological evaluation of granulomatous skin lesions and their etiologica...

IMPORTANCE In the limited number of Crohn disease cases involving the head and neck, there is a predilection for mucosal surfaces and rare reports of involvement in the postauricular region. To our knowledge, in all previously reported cases involving the head and neck, the patients had a known diagnosis of Crohn disease. OBSERVATIONS This case describes a 10-year-old boy with a history of ps...

Sarcoidosis is a multisystemic granulomatous disease of unknown aetiology that usually presents with bilateral hiliar adenopathies, pulmonary infiltrations, and ocular and cutaneous lesions. The specific cutaneous lesions, or granulomatous, are produced in from 9% to 37% of patients with systemic sarcoidosis. Nevertheless, few patients have been described having specific lesions from sarcoidosi...

Intravesical instillation of Bacillus Calmette-Guerin (BCG) hasbecome an established adjuvant treatment for superficial bladdercarcinoma. This treatment is associated with a relatively high rateof side effects which are mostly reversible spontaneously or canbe treated symptomatically. Serious systemic side effects are lessfrequent. One of rare complications is gran...

Sarcoidosis is a multisystem granulomatous disease of unknown etiology and pathogenesis with a chronic course characterized by multiple remissions and relapses. Besides a brief review of relevant literature, this paper reports on a 70-year-old Saudi male patient who presented with a rare form of cutaneous sarcoidosis masquerading as psoriasis. Physical examination revealed presence of multiple,...

Sir, Contact of the skin with metals can induce several types of cutaneous reactions, mainly eczematous skin lesions. However, the increasing tendency to use metallic implants in the skin, mainly by the young populations, is leading to the appearance of other types of cutaneous reactions that can be difficult to differentiate from other infectious and noninfectious cutaneous disorders. We repor...

Cutaneous botryomycosis is a chronic focal infection characterized by a granulomatous inflammatory response to bacterial pathogens such as Staphylococcus aureus. Treatment requires antibiotic therapy and may also require surgical debridement. We employed topical heat therapy and oral minocycline. The lesions became flattened and pigmented after 1 month. We consider that this simple treatment ca...